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Lead Scientist in Medicinal Chemistry

2 months ago


Menlo Park, California, United States Hexagon Bio Full time

About Hexagon Bio

Hexagon Bio utilizes a genomics-driven platform and insights into the evolution of natural products to create innovative therapies for human ailments. Our algorithms pinpoint gene clusters that encode the necessary machinery for producing specialized metabolites, which can be targeted against human disease. This distinctive platform enables us to generate novel chemical leads based on these discoveries. We harness data science, genomics, synthetic biology, and automation to identify potent, evolutionarily optimized small molecules and their corresponding targets from fungal genomes, applying medicinal chemistry to refine these compounds into transformative therapies.

We are enhancing our medicinal chemistry division and have an opening for a Principal Scientist. In this role, you will collaborate closely with teams in natural products chemistry and biology to initiate new drug discovery projects. This position offers an exciting opportunity to act as a project leader from inception through investigational new drug (IND) submission. You will guide a team of medicinal chemists, collectively designing and synthesizing optimized candidates suitable for human clinical trials. This role provides significant career advancement opportunities through engagement with senior leadership and cross-functional collaboration across various scientific fields at Hexagon Bio.

Key Responsibilities:

  • Design and develop new drug candidates and their synthetic pathways
  • Oversee chemistry teams, both in-house and external
  • Lead a skilled medicinal chemistry team with direct reports
  • Act as a project lead for drug discovery initiatives
  • Collaborate across functions to propel Hexagon Bio's pipeline forward

Qualifications:

  • Ph.D. in organic or medicinal chemistry with over 7 years of experience in an industrial medicinal chemistry environment
  • Proven ability to lead teams and manage projects
  • Demonstrated success in advancing scientific projects
  • Willingness to work at our laboratories

What We Provide:

  • A flexible and dynamic work environment that encourages personal growth; Hexagon nurtures the unique strengths of employees at all levels and facilitates mobility across departments.
  • Regular company-wide meetings to share updates, rooted in our values of transparency and designed to foster collaboration, curiosity, and open communication.
  • Discretionary paid time-off policy along with paid holidays
  • Competitive salary and comprehensive benefits package, including medical, dental, and vision insurance, with additional voluntary benefits.
  • Equity options and a 401(k) plan.
  • Opportunities for rapid career progression for motivated individuals.
  • Access to scientific conferences nationwide throughout the year.
  • A variety of amenities at our business park, including fitness facilities, recreational activities, and convenient services.
  • Engagement opportunities within the Hexagon community through team-building events.

Hexagon Bio is committed to creating a diverse workplace and is an equal opportunity employer. All applicants will be considered without regard to race, color, ethnicity, veteran status, religion, national origin, marital status, political affiliation, age, sex, sexual orientation, disability status, or any other non-merit factors.