Senior Bioinformatics Specialist for Genomics and Transcriptomics
3 weeks ago
This Senior Bioinformatics Specialist role is a critical part of our team, focused on advancing genomics and transcriptomics research through expert data analysis and curation.
Main Responsibilities:
- Curate and standardize GWAS summary statistics datasets to ensure accuracy and consistency.
- Annotate genomic variants using established tools and databases.
- Map SNPs to genes and determine their functional relevance.
- Lead the analysis of transcriptomic datasets, including bulk and single-cell RNA sequencing, to derive actionable insights.
- Collaborate with research teams to understand specific data requirements and applications.
- Maintain and contribute to project codebases.
To succeed in this role, you will need:
- A Master's degree with 1+ year of experience or a PhD in quantitative sciences (Bioinformatics, Computer Science, Computational Genetics, Mathematics, Statistics, or related field).
- Proven capability in designing and implementing bioinformatics workflows and corresponding GitHub codebase repositories.
- Expertise in R programming and comfort operating in Unix/Linux and High-Performance Computing (HPC) environments.
- Familiarity with genome-wide association studies, particularly fine mapping and colocalization from GWAS summary data.
- Hands-on experience in curating and processing transcriptomic datasets, especially bulk and single-cell RNA-Seq, with the ability to conduct downstream analyses.
- Knowledge and proficiency in basic statistical concepts, such as p-value, odds ratio, effect size, multiple testing correction, and Bayesian approaches for colocalization analysis.
- Prior experience in immunological diseases or rare disease genetics is beneficial.
Collabera is a global digital solutions company providing software engineering solutions for leading organizations in tech-forward industries. With roots serving top businesses in Technology, Financial Services, Telecom, and Healthcare, we operate across 60 locations in 11 countries, serving 30% of the Fortune 500 companies and consistently exceeding industry growth rates by 3-4x.
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