Computational Chemist

Job Title: Computational Chemist

Job Summary:

We are seeking a highly skilled Computational Chemist to join our team at Gate Bioscience, Inc. as a key member of our drug discovery team. The successful candidate will play a crucial role in developing optimization strategies for our most important drug discovery campaigns.

Key Responsibilities:

• Develop optimization strategies: The Computational Chemist will review experimental results and develop SAR hypotheses for activity, selectivity, and properties, and make suggestions to improve the profiles of our leading molecules.
• Collaborate with cross-functional teams: The ideal candidate will work closely with biochemistry, structural biology, and functional genomics to bring insights from protein-protein and protein small molecule modeling to further enhance our understanding of the novel mechanism of molecular gates.
• Lead computational chemistry initiatives: This role will spearhead modeling initiatives and strategically apply computational chemistry expertise across all stages of a program, including target selection, target validation, lead generation, and lead optimization.
• Utilize informatics and modeling techniques: The successful candidate will utilize various informatics and modeling techniques to analyze large datasets and accelerate the evolution of drug discovery leads as well as enhance our chemical library.
• Identify gaps in current methodologies: The ideal candidate will identify gaps in current methodologies, be able to implement new technologies, and lead the internalization of promising approaches.
• Lead capability build and working groups: This role will lead aspects of our capability build and working groups toward our future-state vision of computational drug discovery at our company.
• Communicate effectively: The successful candidate will effectively communicate with colleagues and stakeholders, create and present research updates, and provide strategic input to team/company meetings.

What We Offer:

We offer a competitive salary range of $170,000 - $270,000, equity in the company, a robust benefits package, 401(k) program with employer match, and the opportunity to be a part of ground-breaking research.

Gate Bioscience, Inc. is an equal opportunity employer.