Director of Pharmacokinetics and ADME Research

2 weeks ago

Burlingame, California, United States Corvus Pharmaceuticals Full time

Job Title: Director of Pharmacokinetics and ADME Research

Location: Burlingame, CA

We are seeking a highly motivated and experienced Director of Pharmacokinetics and ADME Research to lead our preclinical studies and evaluate the pharmacokinetics and ADME properties of novel therapeutic candidates. In this role, you will play a critical role in guiding drug discovery and development teams to ensure successful transition of candidates from preclinical to clinical phases.

Key Responsibilities:

  • Lead the design, implementation, and interpretation of preclinical PK/ADME studies in support of oncology and immunology therapeutic programs.
  • Develop and execute PK/ADME strategies to evaluate the drug-like properties of small molecules, biologics, and new modalities.
  • Collaborate with cross-functional teams (including pharmacology, toxicology, medicinal chemistry, and clinical development) to integrate PK/ADME data into decision-making.
  • Provide scientific and technical expertise in the selection and optimization of lead candidates based on PK/ADME profiles.

Requirements:

  • PhD or equivalent in Pharmacokinetics, Pharmaceutical Sciences, Drug Metabolism, or a related field.
  • 10+ years of experience in non-clinical PK/ADME, with a significant portion in cancer and immunology therapeutics.
  • Deep understanding of PK/ADME principles and hands-on experience with in vitro and in vivo models.
  • Demonstrated expertise in drug development from lead optimization through preclinical and clinical phases.
  • Experience working with biologics and small molecules in oncology or immunology.
  • Familiarity with regulatory requirements and guidelines (FDA, EMA) for PK/ADME data submission.
  • Strong leadership, project management, and team collaboration skills.
  • Excellent written and verbal communication skills, with the ability to convey complex scientific concepts to diverse audiences.

About Corvus Pharmaceuticals:

Corvus Pharmaceuticals is a biopharmaceutical company focused on the development of novel therapeutics for the treatment of cancer and immune-related disorders. We are committed to advancing the field of pharmacokinetics and ADME research and are seeking a talented individual to join our team.

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