Biologics Discovery Scientist

6 days ago


MA United States PharmaEssentia U.S.A. Full time
About the Role

We are seeking a highly skilled Antibody Discovery Scientist to join our Biologics Platform team at PharmaEssentia U.S.A. This is a highly scientific position that requires in-depth knowledge and expertise in molecular biology and yeast display technology.

Key Responsibilities
  • Collaborate with structural and computational biologists to design and build display libraries for antibody, cytokine, and TCR-based protein biotherapeutics.
  • Conduct selection campaigns to identify lead molecules against various targets.
  • Evaluate scientific strategies, review data in real time, and make adjustments to ensure successful delivery of yeast display discovery campaigns.
  • Participate in project teams and identify critical experiments to accelerate drug discovery programs.
  • Provide technical expertise and advice to team members, fostering a culture of continuous learning and growth.
  • Assess and implement new technologies into the existing workflow to inspire creativity and contribute to an innovative product portfolio.
Qualifications
  • PhD in molecular biology, biological engineering, or related biological science disciplines with 2+ years of industrial experience in Biologics discovery function.
  • Strong hands-on experience with yeast display technology and antibody lead discovery and optimization.
  • Proficiency in molecular biology and flow cytometry skills, including multi-parameter analysis and sorting.
  • Strong understanding of antibody structure, function, and engineering.
Preferred Qualifications
  • Experience in single B cell antibody technology.
  • Proficient in NGS antibody library output analysis.
  • Protein design and modeling experience using RoseTTAFold, AlphaFold, or equivalent.

At PharmaEssentia U.S.A., our goal is to develop innovative biotherapeutics that improve patient outcomes. By joining our team, you will contribute to advancing transformative therapies in Oncology, Hematology, and Immunology disease areas.

We are committed to fostering a culture of innovation, collaboration, and continuous learning. If you are a motivated and skilled scientist with a passion for biologics discovery, we encourage you to apply for this exciting opportunity.


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