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Scientific Research Director

2 months ago

New York, New York, United States Memorial Sloan Kettering Cancer Center Full time
Job Title: Scientific Research Director

We are seeking a highly skilled and experienced Scientific Research Director to lead our RNA Therapeutics Laboratory at Memorial Sloan Kettering Cancer Center.

Job Summary:

The successful candidate will oversee the creation of an independent mRNA vaccine pipeline, encompassing vaccine platform optimization and GMP manufacturing for clinical use. They will lead/oversee RNA vaccine design and process development, quality control, and transfer of assays to the GMP-Therapeutics Core Facility.

Key Responsibilities:
  • Oversee the development of an mRNA vaccine pipeline, including platform optimization and GMP manufacturing
  • Lead/oversee RNA vaccine design and process development, including modifications to optimize the mRNA template, structure, stability, and production
  • Develop and optimize analytical assays to evaluate the quality and efficacy of mRNA vaccines
  • Transfer assays to the GMP-Therapeutics Core Facility and support vaccine manufacturing
  • Provide oversight and leadership to technical staff
  • Set the short-, medium-, and long-term scientific directions of the laboratory
  • Operational responsibilities include oversight of advanced methods development, scientific consultation, and liaison with the scientific community
  • Responsible for financial and human resource management, including hiring, training, mentoring, and staff career development
Requirements:
  • Ph.D. in immunology, cell biology, biochemistry, biophysics, or a related discipline
  • 5+ years of experience in the academic or commercial sector
  • Hands-on experience working in experimental mRNA vaccine biology and clinical development of GMP-grade mRNA vaccines
  • Expertise in mRNA customization, synthesis, and purification
  • Expertise in mRNA-LNP platforms, cGMP process flow, and analytical panel development
  • Excellent interpersonal, written, and oral communication skills
  • Experience managing laboratory staff and overseeing day-to-day laboratory operations
What We Offer:
  • A highly experienced and skilled scientist with a sharp focus, attention to detail, and good decision-making skills
  • A quick learner and strong problem-solver who sees the forest and the trees and can quickly identify anomalies in data and uncover their source
  • Adept at multitasking, planning, prioritizing, and re-prioritizing work to meet goals and commitments with minimal supervision in a dynamic environment
  • A highly motivated person capable of building strong relationships within the lab and with internal and external collaborators
  • An outstanding communicator and clear presenter, capable of determining how best to reach different audiences and executing such communications
  • A creative thinker and strategic planner who can think outside the box
  • Consistently achieving results, even under tough circumstances
Additional Information:
  • Location: Memorial Sloan Kettering Cancer Center, NYC
  • Schedule: Monday - Friday, 9 am - 5 pm
  • Reporting to: Director, Center of Cancer Vaccines

Salary Range: $109,000- $174,000