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Senior Research Scientist
2 months ago
About R&D Partners
R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.
Job Summary
We are seeking a highly skilled Senior Research Scientist to join our team at R&D Partners. The ideal candidate will have significant laboratory experience and an excellent understanding of analytical chemistry principles.
Key Responsibilities
- Process Characterization
- Contribute to process characterization efforts for the company's pneumococcal conjugate vaccine program.
- Develop and implement new laboratory workflows and analyses beyond established procedures when appropriate.
- Conjugation Process Development
- Purify polysaccharides and conjugates using a variety of methods including dialysis, size-exclusion chromatography, and tangential flow filtration (TFF).
- Analyze polysaccharides and conjugates with a variety of analytical methods.
- Design, execute, and troubleshoot experiments with minimal guidance.
- Team Collaboration
- Advise team members on experimental design, interpretation of results, and troubleshooting.
- Model and train team members on best practices for adherence to protocols and data management.
- Serve as a subject matter expert during tech transfer of conjugation processes to contract manufacturing organizations.
- Record Keeping and Communication
- Maintain highly organized records to enable optimization and assessment of reproducibility.
- Attend team meetings ready to provide updates on conjugation development progress.
Requirements
- PhD in chemistry, biochemistry, or related field with 2-5+ years of industry experience, MS with 5-8+ years, or BS with 10+ years of experience.
- Strong biochemistry and organic chemistry knowledge base underpinning several years' experience preparing bioconjugates.
- Proficiency with small- and large-scale techniques for purification of bioconjugates, including tangential flow filtration.
- Proficiency in a variety of techniques for bioconjugate analysis such as colorimetric assays, HPLC, and SEC-MALS.
- Sufficient knowledge of analytical principles to develop fit-for-purpose analytical methods as needed and provide cross-functional feedback on draft analytical methods.
- Experience with Design of Experiments is desirable.
- Experience with chemical modification of polysaccharides is desirable.
Compensation
$120,000- $160,000 annually
R&D Partners is an equal-opportunity employer.
