Senior Research Investigator/Research Investigator QSP&PBPK Methods Expert

2 weeks ago


Somerville, Massachusetts, United States Bristol-Myers Squibb Full time
Transforming Patients' Lives through Science

Bristol-Myers Squibb is a leading pharmaceutical company dedicated to discovering and developing innovative treatments for patients worldwide. We are seeking a highly skilled Quantitative Systems Pharmacology and Physiologically Based Pharmacokinetics Specialist to join our team.

About the Role

We are looking for a talented scientist with expertise in model calibration algorithms and pipelines to lead our QSP&PBPK team. The successful candidate will bring advanced mathematical or statistical training and experience developing customized Bayesian algorithms. Experience with virtual population approaches is highly desired, but not required.

Responsibilities
  • Provide leadership for existing model calibration and computing capabilities and future model, technology, and algorithm innovation and development
  • Advance novel and rigorous methodologies for model variability calibration, sensitivity analysis, and prediction uncertainty characterization
  • Assist therapeutic area expert modelers to accelerate efforts and ensure timely model development and calibration to impact drug development programs
  • Maintain, advance, and coordinate codebases and documentation for data integration and analysis as well as model simulation, characterization, and calibration
  • Partner with external groups to accelerate the internal efforts in key technology areas
Requirements
  • Ph.D. in Statistics, Applied Mathematics, Biomedical/Chemical Engineering, Computer Science, Physics, Computational Biology, or related field
  • M.S. in appropriate field with significantly more experience may be considered
  • Excellent understanding of the theory and principles in optimization and global sensitivity analysis
  • Expertise in virtual population methods or related concepts and strategies for model calibration
What We Offer

Bristol-Myers Squibb offers a competitive salary range of $132,000-$182,000, plus incentive cash and stock opportunities (based on eligibility). We also offer a comprehensive benefits package, including medical, dental, and vision insurance, 401(k) matching, and paid time off.

Join our team and be part of a dynamic and innovative company that is transforming patients' lives through science.



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