Senior Bioprocess Engineer

2 days ago

Boston, Massachusetts, United States Arcaea Full time
Job Title: Senior Bioprocess Engineer

Arcaea is a biology-first beauty company that is revolutionizing the beauty and personal care industry with pioneering ingredients, products, and stories accessible uniquely through biology.

We are seeking an experienced Senior Bioprocess Engineer to join our team and play a critical role in developing our ingredient toolset for the beauty and personal care industry. As a member of the Arcaea team, you will be responsible for leading Arcaea's downstream process development and scaling up activities.

Key Responsibilities:
  • Lead the design, development, and implementation of downstream processes for the purification of bioactive ingredients
  • Apply your proficiency in a diverse range of downstream unit operations, such as chromatography, membrane separation processes, centrifugation, lyophilization, spray drying, and other relevant techniques
  • Conduct hands-on troubleshooting, process feasibility, and process optimization experiments in relation to downstream purification and recovery processes
  • Build a science-based understanding of processes to define critical process parameters and establish acceptance criteria
  • Apply statistical data analysis in development, including design of experiments (DoE), multivariate analysis
  • Assist with cost modeling analyses as needed
  • Participate in tech-transfer activities with CDMO and CMOs and build strong relationships with collaborating companies
  • Showcase your proven ability to scale up bioprocesses from laboratory-scale to pilot-scale and eventually to full-scale production
  • Maintain meticulous documentation of experimental procedures, results, and process parameters
  • Ensure compliance with industry standards and regulatory guidelines governing the production of cosmetic ingredients
  • Develop technical insights based on research and scientific literature
  • Stay informed about the latest advancements in downstream processing technologies, assessing their applicability to elevate our processes
  • Communicate technical information to internal teams and/or external parties in the form of oral and written correspondence, presentations, and reports
  • Work effectively and efficiently on a tight deadline without drama or ego
Requirements:
  • MS/PhD in chemical engineering, life sciences, biotechnology, or equivalent experience
  • 5+ years of experience in downstream processing, with a variety of unit operations
  • Successful track record of developing and scaling up industrial biotech DSP processes
  • Proven ability to manage projects
  • Experience with tech transfer to CDMO/CMOs
  • Proficiency in process simulation and modeling tools is advantageous
  • Strong problem-solving and analytical skills
  • Highly independent with the ability to work with cross-functional teams in a fast-paced environment
  • Delivering on projects, on time
  • Effective communicator, can explain complex science in layman terms
  • Strong interpersonal skills
  • Startup experience preferred

The full compensation package is based on candidate experience.

We are committed to diversity, equality, and inclusion in all our practices. It is the policy of Arcaea to provide equal employment opportunities to all employees and employment applicants.

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