Lead Scientist, Genomic and Cellular Biomarkers
2 weeks ago
Position Overview:
We are seeking a highly skilled and dynamic scientist with extensive laboratory expertise in genomic technologies to join the Cellular Biomarkers Genomics team within the Biomarker and Bioanalytical Platform (BBP) department. This role is pivotal in the development and application of genomic and proteogenomic biomarker assays for clinical research.
Key Responsibilities:
As a technical authority in genomic and proteogenomic technologies, you will be responsible for generating data that enhances our understanding of disease variability, mechanisms of drug action, and patient treatment responses at the molecular level. Your expertise will be applied through advanced genomic technologies, including Next Generation Sequencing (NGS), Olink Proximity Extension Assay (PEA), single-cell analysis, qPCR, and dd-PCR.
Method Development and Validation:
You will oversee all facets of method development, troubleshooting, validation, and sample analysis for clinical studies that require genomic and proteogenomic endpoints. This includes reagent selection, sample preparation, acquisition, and data processing, ensuring compliance with GCLP regulations and adherence to standard operating procedures (SOPs).
Collaboration and Innovation:
Collaborate with cross-functional teams, including Translational Research, Clinical Biomarkers, and regulatory affairs, to provide scientific expertise that supports project advancement. You will also evaluate novel genomic and proteomic techniques to inform biomarker development and validation.
External Engagement:
Support strategic partnerships with academic institutions and contract research organizations (CROs) to leverage cutting-edge technologies and biomarker expertise.
Qualifications:
We are looking for candidates with a Ph.D. in a relevant scientific discipline (e.g., Biochemistry, Cell/Molecular Biology, Genetics, Genomics, or related fields) and a minimum of 1-2 years of post-PhD experience, or a B.S./M.S. degree with 5-10 years of relevant experience. Proficiency in current genomic analytical platforms and experience in the design and interpretation of data from various genomic technologies is essential.
Preferred Skills:
Hands-on experience with Next Generation Sequencers and automated liquid handling systems is advantageous. Candidates should demonstrate strong project management skills, attention to detail, and the ability to communicate complex scientific concepts effectively.
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Collegeville, Pennsylvania, United States GlaxoSmithKline Full timeSite Name: USA - Pennsylvania - Upper ProvidencePosted Date: Aug We have an exciting opportunity for a highly motivated, agile, and experienced scientist with lab level expertise in genomic technologies to join the Cellular Biomarkers Genomics group within the Biomarker and Bioanalytical Platform (BBP) department based in Collegeville, PA. Our group is...
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