Bioinformatics Research Scientist

6 days ago


Boston, Massachusetts, United States Lifelancer Full time

Company Overview

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Terray Therapeutics is a venture-backed biotechnology company led by pioneers in artificial intelligence, synthetic chemistry, automation, and nanotechnology. Our mission is to propel drug discovery into the information age with our closed-loop system generating precise chemical datasets at an unrivaled scale.

Position Summary

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We are seeking a motivated and experienced scientist to join our Molecular Design group within the Computational and Data Sciences (CDS) team. The ideal candidate will design combinatorial libraries for our platform and contribute to hit-to-lead and lead optimization efforts across multiple drug discovery programs.

Core Responsibilities

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  • Design focus libraries using proprietary ML models and computational tools.
  • Develop metrics to assess and improve library designs.
  • Extract insights from ultra-large proprietary screening datasets in collaboration with data scientists and cheminformaticians.
  • Contribute to the design of small molecules with in-house high-throughput computational tools using structure-based and ligand-based models.
  • Communicate molecular design strategy and outcomes to teams across the company.">

Requirements

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  • A BS/MS/Ph.D. in computational, organic, or medicinal chemistry, or a related field.
  • Experience designing small-molecule libraries for virtual screens, DEL screens, and/or HTS.
  • Experience triaging large data sets from virtual screens, DEL screens, and/or HTS.
  • Proficient in Python and the PyData stack (numpy, pandas, scipy, scikit-learn, etc.).
  • Familiarity with RDKit and molecular simulation suites (Schrodinger, MOE, etc.) and docking programs (AutoDock Vina, rDock, etc.).">

Benefits

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Competitive salary $132,000-$198,000 annually depending on seniority; participation in the Company's option plan; 3% retirement safe harbor contribution; fully-paid medical, dental, vision, life, and disability benefits.

About Terray

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At Terray, we believe that innovation starts with collaboration. As a part of our team, you'll be working alongside talented individuals who share your passion for transforming the world through science.



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