Chemist - Oligonucleotides Specialist
2 weeks ago
The Oligonucleotides Chemist is a critical role within our organization, responsible for ensuring the successful transfer of new products from development to manufacturing. This position requires a strong scientific background and expertise in oligonucleotide production, including operation of automated synthesis equipment and post-labeling techniques.
Key Responsibilities- Operate automated synthesis equipment, including ABI and AKTA 10 & 100, to produce high-quality oligonucleotides.
- Conduct post-labeling oligonucleotides with different chemistries to meet specific product requirements.
- Fulfill all training requirements for oligo mixing, instrument use, and necessary oligo production tasks, following regulatory guidelines.
- Operate analytical instruments, including HPLC, UHPLC, LC-MS, UV-Vis, and fluorescent spectroscopy, to characterize reagents and ensure product quality.
- Process production materials using bench techniques and lab instrumentation, including Prep HPLC, pH probe, balances, NanoDrop, and rotary evaporators.
- Batch production, prepare protocols, and revise process procedures following ISO-9001 quality system standards.
- Maintain inventory of raw materials and final mixtures to ensure efficient production and minimize waste.
- BS/MS degree in Chemistry, Biology, or related field.
- Minimum 3-5 years' experience in the life science industry, with expertise in oligonucleotide production and automated synthesis equipment.
- Strong synthetic chemistry knowledge and scale-up experience, with ability to think logically and prioritize tasks.
- Excellent oral and written communication skills, with ability to collaborate with team members and communicate effectively with supervisors and colleagues.
As a valued member of our team, you will enjoy a comprehensive benefits package, including medical, prescription drug, dental, and vision coverage, as well as access to a Health Savings Account (HSA) and Flexible Spending Account (FSA). You will also be eligible for employee assistance programs, fertility benefits, and adoption assistance programs.
What We Offer- Competitive salary and bonus structure.
- Opportunities for professional growth and development.
- A dynamic and inclusive work environment.
- A comprehensive benefits package.
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