Lead Research Scientist

1 week ago


Exton, Pennsylvania, United States Frontage Laboratories Full time
Job Overview

Lead Research Scientist

At Frontage Laboratories, Inc., we are seeking a dedicated and skilled Lead Research Scientist to join our team. In this role, you will be responsible for executing LC-MS/MS bioanalytical assays along with comprehensive data analysis, quality control, and interpretation for toxicokinetic and pharmacokinetic assessments. You will also validate innovative scientific methodologies, assays, and reports.

Key Responsibilities:

  • Conduct method development, transfer, and validation for both large molecules (such as proteins and antibodies) and small molecules, adhering to GLP and ICH standards.
  • Perform assays for various drug products, including but not limited to antibody-drug conjugates, proteins, biomarkers, and peptides utilizing advanced techniques such as HPLC, UPLC, and LC-MS.

Qualifications:

  1. A Master of Science degree or its foreign equivalent in Chemistry, Biochemistry, or a related discipline.
  2. A minimum of 2 years of experience in a similar role or relevant research experience, which should encompass enzymatic assay development and execution, protein expression, purification techniques (including LC, IMAC, IEX, SEC), and enzyme kinetics using methods such as stopped-flow and RFQ-EPR.
  3. Demonstrated proficiency in High Performance Liquid Chromatography (HPLC) and Liquid Chromatography Mass Spectrometry (LC-MS).

This position requires a commitment of 40 hours per week, Monday through Friday. We encourage qualified candidates to explore this opportunity to contribute to our innovative research initiatives.



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