Clinical Director

1 month ago


Collegeville, Pennsylvania, United States Pfizer Full time
ROLE SUMMARY

The Clinical Lead (CL) will be the key figure driving clinical research for metabolic diseases at Pfizer. This individual will be responsible for creating the overarching strategy for early clinical development programs, focusing on innovative design, medical and scientific excellence, and the highest ethical standards.

The CL will lead clinical development strategy and program execution of research projects, with a particular focus on obesity and associated conditions. This includes translating pre-clinical observations into clinical experiments and studies designed to demonstrate proof of pharmacology, proof of mechanism, and proof of concept for new candidate medicines.

The CL will apply deep medical and clinical knowledge to translate clinical research ideas into high-quality decision-making data, working closely with subject matter experts from statistics, clinical pharmacology, and other team members.

The CL serves as a single clinical development point of contact to the Research Project Leader for each assigned project.

ROLE RESPONSIBILITIES
  • Uses deep medical and scientific knowledge and expertise to contribute to the selection of targets for progression from chemical/biologic synthesis to testing in humans.
  • Leads the creation of the clinical development plan from pre-clinical stages through to proof of concept.
  • Guides clinical team members to ensure excellence in development and translation of clinical research plans into efficiently delivered studies.
  • Creative in the conception of novel study designs and collaborates with the Clinician and Operations Manager to ensure these novel designs are optimized for operational effectiveness to ensure timely and cost-effective delivery.
  • Oversees the design and execution of clinical research studies, including development of outline/core elements prepared by Clinicians or other clinical team members.
  • Accountable for development of clinical documents, such as protocol, clinical report, and clinical components of regulatory submissions.
  • Serves as a Medically Qualified Individual (MQI) at Pfizer, reviewing clinical trial data for safety signal identification and tracking.
  • Provides input to the operational strategy and feasibility of clinical research studies, in conjunction with the Development Director, Operations Manager, and Clinician; accountable for final decision.
  • Establishes relationships with key clinical experts/sites and uses this information to advise the clinical team on site selection.
  • Flexible in supporting a dynamic research portfolio; may need to manage multiple programs in parallel, depending on the development stage of the programs.
  • Contributes to technical and protocol review committees across the portfolio.
QUALIFICATIONS
  • MD or MD/PhD (or equivalent degree(s)) with relevant postgraduate clinical training.
  • Approximately 8-10 years relevant experience.
  • Preference for established record in execution of clinical trials in the pharmaceutical industry environment; experience in managing complex projects.
  • Firm understanding of the drug development process with particular emphasis on early clinical development.
  • Scientific excellence; possesses deep knowledge of integrated metabolism biology and metabolic diseases such as obesity, diabetes, and cardiovascular/cardiometabolic disorders.
  • Superior clinical ability with relevant disease area knowledge and experience.
  • Ability to design, initiate, and conduct effective clinical studies applying novel principles as appropriate, and integrating these plans into a cohesive overall clinical development strategy.
  • Strong understanding of the complexities and current developments in the relevant disease/technical area, and skillfully applies this knowledge to drug development.
  • Firm understanding of clinical regulatory requirements, and knowledge of GCP and ICH guidelines.
  • Experienced with ownership of budgets and sound financial risk management.
  • Ability to review and understand emerging data and proactively implement measures to ensure delivery of quality study results.
  • Skilled communicator and team leader, able to clearly articulate ideas and integrate feedback.
  • Ability to navigate a complex matrixed environment and manage teams that are diverse in terms of expertise, background, and geography.
PREFERRED QUALIFICATIONS
  • Board eligibility/certification in Internal Medicine, with subspecialty training in obesity medicine and/or endocrinology (or analogous relevant subspecialty training) preferred.
  • Active medical license preferred.
COMPENSATION

The annual base salary for this position ranges from $213,500.00 to $355,000.00, in addition to participation in Pfizer's Global Performance Plan with a bonus target of 25.0% of the base salary and eligibility to participate in our share-based long-term incentive program.

We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments.

Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday, and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental, and vision coverage.

Learn more at Pfizer Candidate Site - U.S. Benefits | .

Pfizer compensation structures and benefit packages are aligned based on the location of hire.

The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

SUNSHINE ACT

Pfizer reports payments and other transfers of value to healthcare providers as required by federal and state transparency laws and implementing regulations.

These laws and regulations require Pfizer to provide government agencies with information such as a healthcare provider's name, address, and the type of payments or other value received, generally for public disclosure.

Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.

Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address, and the amount of payments made currently will be reported to the government.

If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & EMPLOYMENT ELIGIBILITY

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability, or veteran status.

Pfizer also complies with all applicable national, state, and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.

Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.


  • Clinical Director

    4 weeks ago


    Collegeville, Pennsylvania, United States Penn Psychiatric Center Full time

    Job SummaryWe are seeking a highly experienced and skilled Clinical Director to lead our IBHS program at Penn Psychiatric Center. The successful candidate will be responsible for ensuring that staff providing IBHS are clinically supervised and receive necessary training in accordance with OMHSAS regulations.The Clinical Director will oversee all IBHS program...


  • Collegeville, Pennsylvania, United States GlaxoSmithKline Full time

    Job Description:The Director, External Manufacturing Procurement plays a pivotal role in shaping and executing GSK's procurement strategies for large molecule and vaccine drug substances from our external network. This key role will be at the forefront of managing partnerships with Contract Manufacturing Organizations (CMOs), ensuring that GSK develops...


  • Collegeville, Pennsylvania, United States GlaxoSmithKline Full time

    Job DescriptionWe are seeking a highly motivated and experienced Associate Director to lead our Quantitative Systems Pharmacology (QSP) efforts in the Drug Metabolism and Pharmacokinetics (DMPK) department. The successful candidate will be responsible for developing and applying QSP models to aid in the prioritization, selection, understanding, and...


  • Collegeville, Indiana, United States GlaxoSmithKline Full time

    Accelerate Business Performance across and drive global operational support as a Clinical Development Director at GlaxoSmithKline.The Clinical Sciences Lead is the single point of accountability for the development of the scientific design, medical governance, and interpretation of results of a study. The study designed is expected to fulfill a strategic...

  • Medical Director

    4 weeks ago


    Collegeville, Indiana, United States GlaxoSmithKline Full time

    Job SummaryThe Medical Director - Oncology Clinical Development will lead clinical research activities to advance the development of GSK's oncology portfolio. This role will report to the Executive Medical Director, Clinical Development Lead (CDL), Oncology Clinical Development.Key ResponsibilitiesCollaborate with physicians, scientists, regulatory...

  • Clinical Director

    4 weeks ago


    Collegeville, Indiana, United States Penn Psychiatric Center Full time

    Job SummaryThe Clinical Director at Penn Psychiatric Center will oversee the provision of Intensive Behavioral Health Services (IBHS) to children and adolescents. This role requires a strong clinical background and leadership skills to ensure the delivery of high-quality services.Key ResponsibilitiesEnsure that staff providing IBHS are clinically supervised...


  • Collegeville, Indiana, United States GlaxoSmithKline Full time

    Job DescriptionJob Title: Medical Director Oncology Clinical DevelopmentJob Summary: We are seeking a highly skilled Medical Director to lead our Oncology Clinical Development team. The successful candidate will be responsible for advancing the development of our clinical portfolio and engaging with scientific and medical leaders to generate clinical...


  • Collegeville, Indiana, United States GlaxoSmithKline Full time

    Job DescriptionJob Title: Clinical Development DirectorJob Summary: We are seeking a highly skilled Clinical Development Director to partner with key leaders in global medical science to accelerate business performance across and drive global operational support.Key Responsibilities:Study Design: Develop the scientific design, medical governance, and...


  • Collegeville, United States Penn Psychiatric Center Full time

    Ensuring that staff who provide IBHS are clinically supervised and receive all necessary training in accordance with OMHSAS IBHS regulations. Monitor all IBHS program systems and procedures including but not limited to treatment protocols and intervention, psychiatry services, consumer satisfaction, crisis intervention and all program policies related to...


  • Collegeville, United States GlaxoSmithKline Full time

    Reference #: 406149 Site Name: USA - Pennsylvania - Upper Providence Posted Date: Oct 16 2024 By applying to this role, you will also be considered for other open positions within the Clinical Programming department at GSK. If you prefer not to be considered for multiple opportunities, please flag to our recruitment team. Clinical Programming at GSK GSK...


  • Collegeville, United States GlaxoSmithKline Full time

    Site Name: USA - Pennsylvania - Upper Providence, UK - Hertfordshire - Stevenage Posted Date: Oct 17 2024 We are seeking an Associate Director level, Quantitative Systems Pharmacology Disease Lead for our Drug Metabolism and Pharmacokinetics (DMPK) department. Quantitative Systems Pharmacology (QSP) is a discipline that uses mechanistic mathematical models...


  • Collegeville, Minnesota, United States GlaxoSmithKline Full time

    Job SummaryWe are seeking a highly skilled and experienced Veterinary Medicine Leader to join our team as Senior Director Veterinarian/Laboratory Animal Science and Governance. This role will be responsible for ensuring the health and well-being of laboratory animals used in research at GSK facilities in Pennsylvania and Massachusetts.Key...


  • Collegeville, United States ProCare Therapy Full time

    Job DescriptionJob DescriptionMinimum 1+ years speech therapy experience required.ProCare Therapy is seeking a Speech-Language Pathologist to work in a friendly and supportive school district for the 2024-2025 academic year. The district welcomes candidates from a variety of backgrounds, with a preference for those experienced in school-based settings. To...

  • Nurse Supervisor

    4 weeks ago


    Collegeville, United States Patient First Full time

    Patient First is accepting applications for a Nurse Supervisor in the Collegeville, PA area. Patient First provides a friendly work environment that promotes a team-oriented philosophy.Sign-On Bonus!The responsibilities of this job include, but are not limited to, the following:* Supervising the medical care of all patients from registration to departure;*...

  • Nurse Supervisor-RN

    2 months ago


    Collegeville, United States Patient First Full time

    Patient First is accepting applications for Nurse Supervisor - RN in the Collegeville , PA area. Patient First provides a friendly work environment that promotes a team-oriented philosophy. Sign-On Bonus! The responsibilities of this job include, but are not limited to, the following: Supervising the medical care of all patients from...


  • Collegeville, Minnesota, United States Centurion Health Full time

    About the Role:Centurion Health is seeking a dedicated Psychiatrist to join our team at the State Correctional Institution Phoenix in Collegeville, Pennsylvania.Key Responsibilities:Provide psychiatric evaluation, diagnosis, and treatment for patientsWork under the supervision of the Psychiatric Medical DirectorProvide clinical leadership for a...


  • Collegeville, United States DirectEmployers Full time

    **-$10,000 Sign On Bonus for Full Time!-****-Whatever your needs are, the Director will work with you to create a schedule that works for you!-****We have a** **Registered Nurse** **opportunity open now doing visits in Senior Living communities in** **the Western Montgomery County area.****-Flexible schedules, 1:1 care, and great work/life balance. Join us...


  • Collegeville, United States GlaxoSmithKline Full time

    Reference #: 407054 Site Name: USA - Pennsylvania - Upper Providence Posted Date: Oct 23 2024 Job Purpose GSK's success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel...


  • Collegeville, United States GlaxoSmithKline Full time

    Reference #: 407054 Site Name: USA - Pennsylvania - Upper Providence Posted Date: Nov 13 2024 Job Purpose GSK's success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel...

  • MRI Technologist

    4 weeks ago


    Collegeville, United States Jefferson Outpatient Imaging Full time

    Join an energetic, patient-focused team! Jefferson Outpatient Imaging-Collegeville is currently seeking an experienced MRI Technologist for a Full-time Flex position at our outpatient imaging center located in Collegeville. The Shift is as Follows: Monday- 630am-5pm Tuesday- 830am-5pm Wednesday- 930am-8pm Friday- 830am-5pm JOB SUMMARY :Under the...