Head of In Vivo Pharmacology Lead

4 days ago

Brisbane, California, United States Gate Bioscience, Inc. Full time

{"title": "Head of In Vivo Pharmacology", "description": "Gate Bioscience is a pioneering biotech company revolutionizing the field of molecular gates. Our innovative therapeutics aim to cure diseases by selectively eliminating harmful extracellular proteins at their origin. With a unique approach, we're creating a new class of medicines that have the potential to transform the lives of patients. As a key member of our team, you'll play a vital role in advancing our small molecule programs to IND.

**Key Responsibilities:**

* Lead the In Vivo Pharmacology team in performing critical preclinical PK-PD and efficacy studies across different therapeutic areas
* Design, execute, and analyze pharmacology studies to support the advancement of candidates to the clinic, both in vivo and ex vivo
* Identify, initiate, and manage collaborations with CROs and academic labs as appropriate to driving projects forward
* Serve as a Biology Lead for early-stage program(s), providing hands-on wet lab support as needed, as well as strategic leadership
* Support preparation of regulatory documents

**Requirements:**

* PhD in pharmacology or biological disciplines, with 8-12+ years industry experience
* In-depth in vivo pharmacology experience, particularly in the design and execution of rodent disease models across therapeutic areas
* Demonstrated leadership of teams of in vivo scientists to drive go/no-go decisions
* Extensive experience in managing the design and execution of studies at CROs
* History of translational sciences support for preclinical small molecule programs, including performing ex vivo and in vitro assays
* Compassionate and supportive leader, who believes that in vivo pharmacologists should own their experiments from start to finish (including ex vivo work, data analysis and communication) so that they are fully integrated into project teams
* Direct experience in supporting IND strategy and documentation, including writing relevant pharmacology sections of INDs
* Prior experience working with small molecules and in smaller companies is highly preferred

**What We Offer:**

* Competitive salary range: $170,000 - $195,000
* Equity in the company
* Robust benefits package
* 401(k) program with employer match
* Opportunity to be part of ground-breaking research

Gate Bioscience is an equal opportunity employer and welcomes applications from diverse candidates.

If you're a motivated and experienced leader in in vivo pharmacology, we encourage you to apply for this exciting opportunity to join our team and contribute to the development of innovative therapeutics.

**Apply Now:**

Please submit your application, including your resume and a cover letter, to [insert contact information].

We look forward to hearing from you

**Note:**

Gate Bioscience is a venture-backed company, and this role is subject to the terms and conditions of our employment agreement.

By applying for this position, you acknowledge that you have read and understood the terms and conditions of our employment agreement.

Thank you for your interest in Gate Bioscience

Sincerely,
[Your Name]"}

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