Scientist

4 weeks ago

MA United States Digital Prospectors Full time
Scientist Job Description

We are seeking a highly motivated and experienced Scientist to join our dynamic team at Digital Prospectors. In this position, you will play a pivotal role in the execution and analysis of both in vitro and in vivo assays, addressing key scientific questions that inform our program decisions.

Key Responsibilities:
  • Process tissue samples and perform routine and specialized histological staining techniques; analyze histological samples using image analysis.
  • Develop and implement novel histological and molecular assays to enhance our understanding of disease biology and evaluate therapeutic efficacy across multiple gene therapy programs.
  • Maintain mammalian cell culture and design, perform, and analyze cell-based assays to assess therapeutic responses to drug candidates.
  • Collaborate effectively within cross-functional teams to drive innovation in a patient-focused research environment.
  • Expand scientific knowledge and contribute innovative ideas to product development.
  • Analyze, interpret, document, and present research data to cross-functional teams; communicate progress during team and departmental meetings.
Requirements:
  • Bachelor's or Master's degree with 5+ years of experience, or PhD with 0-2 years of experience in an academic or industry setting.
  • Strong experience with mammalian tissue processing, including fixation, embedding, and sectioning (FFPE and frozen).
  • Proficient in performing histological assays, including immunofluorescence, immunohistochemistry, and specialized tissue-specific stains; experience with fluorescent in situ hybridization is a plus.
  • Skilled in microscopy (brightfield, fluorescence) and image analysis, with experience in platforms like Indica HALO being advantageous.
  • Experience in mammalian cell culture, including plasmid transfections and viral transductions.
  • Familiarity with cell-based and molecular biology assays (i.e., qPCR, ddPCR, dPCR, Western blotting, immunocytochemistry, and ELISA).
  • Proficient in data analysis, particularly using GraphPad Prism.
  • Excellent communication skills and the ability to engage effectively in cross-functional teams within a dynamic, fast-paced environment.
  • Self-motivated, detail-oriented, and equipped with strong problem-solving abilities.

As a valued member of our team, you will have the opportunity to work on cutting-edge projects and contribute to the development of novel therapeutics for rare diseases. If you are passionate about making a significant impact in the field of rare disease research, we would love to hear from you today.

At Digital Prospectors, we are committed to fostering a diverse, equitable, and inclusive work environment. We invite you to join us in our mission to make a difference in the lives of patients and families affected by rare diseases.

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