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Principal Scientist Molecular Interactions and Analytics
2 months ago
We are seeking a highly skilled and experienced Principal Scientist to join our team at Bristol-Myers Squibb. As a key member of our Molecular Interactions and Analytics Group, you will play a critical role in supporting our biophysical characterization of drug candidates.
Key Responsibilities- Perform and analyze kinetic and thermodynamic studies of antigen-antibody interactions using surface plasmon resonance (SPR) with sufficient rigor to both evaluate and characterize the antigen-antibody interactions under study.
- Perform epitope binning studies using SPR.
- Perform and analyze kinetic and thermodynamic studies of antigen-antibody interactions using solution-based methods such as Kinetic Exclusion Assay or non-traditional SPR experiments.
- Drive the development of novel biophysical assays.
- Contribute as an essential and reliable component to help drive projects to a successful conclusion with a high level of motivation.
- Interact productively with scientifically diverse research teams, including clear and concise presentation of data through oral presentations and written reports/communications.
- Bachelor's Degree 8+ years of academic / industry experience
- or
- Master's Degree 6+ years of academic / industry experience
- or
- PhD 4+ years of academic / industry experience
- Position requires a background in Biophysics, Chemistry, Biochemistry or related field with a Ph.D. and 4+ more years of professional experience, or a master's degree with 6+ years or greater of relevant experience in a pharmaceutical or biotechnology research environment.
- Knowledge of surface plasmon resonance and experience with the operation of diverse SPR instrumentation.
- Knowledge of KinExA experiments and experience with the operation of KinExA instrumentation a plus.
- Demonstrated ability to interpret biophysical binding data.
- Demonstrated ability to communicate and present biophysical binding data to scientifically diverse teams.
- Demonstrated ability to creatively solve problems related to biophysical experimental design.
- Knowledge and understanding of the application of statistical principles and statistical software (e.g. GraphPad) required.
Bristol-Myers Squibb offers a competitive compensation package, including a salary range of $121,000 - $167,200, plus incentive cash and stock opportunities (based on eligibility). We also offer a comprehensive benefits package, including medical, pharmacy, dental and vision care, wellbeing support, financial well-being resources, and more.
About Bristol-Myers SquibbBristol-Myers Squibb is a global biopharmaceutical company dedicated to transforming patients' lives through science. We are committed to advancing the field of biopharmaceuticals and improving the lives of patients worldwide. Our team is passionate about innovation, collaboration, and making a meaningful impact in the lives of others.
