Upstream Manufacturing Specialist

3 hours ago


Piscataway, New Jersey, United States Global Life Science Hub Full time
Job Opportunity

Global Life Science Hub is partnering with a leading biopharmaceutical company to fill a critical role in their commercial manufacturing organization. The company has achieved significant milestones, including two FDA approvals, and is expanding its operations to a new state-of-the-art facility in New Jersey.

We are seeking an experienced Upstream Manufacturing Associate to support the scale-up of manufacturing efforts. The ideal candidate will have a strong background in cell culture, particularly with CHO cells, and experience working with perfusion-based bioreactor systems.

Key Responsibilities:
  • Lead and execute upstream batches, including mammalian cell culture with a focus on CHO cell lines.
  • Design, optimize, and troubleshoot cell culture processes in batch, fed-batch, and perfusion bioreactor systems.
  • Maintain and scale up cell culture operations to support clinical and commercial manufacturing.
  • Collaborate with cross-functional teams to transfer processes from development to GMP manufacturing.
  • Perform cell culture maintenance, monitoring, and harvesting in compliance with regulatory standards.
  • Analyze data, prepare technical reports, and present findings to project teams.
  • Implement continuous improvements in bioprocessing techniques to enhance productivity and product quality.
  • Adhere to safety and regulatory guidelines to ensure a high-quality manufacturing environment.
Requirements:
  • BSc/MSc in a life science related field with 3+ years experience in a pharma/biotech organization.
  • Expertise in mammalian cell culture with a focus on CHO cells.
  • Experience with perfusion bioreactors.
  • Previous background in bioreactor operations including scale-up from Clinical to Commercial.
  • Strong familiarity with GMP regulations.

Global Life Science Hub is a niche Life Science headhunting firm, placing professionals across Europe and the US for a variety of Biotechnology, Pharmaceutical, and CDMO companies. If you're interested in this opportunity, please apply below. For more vacancies, visit our website.



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