Research Scientist
2 weeks ago
Immunology Expertise Sought
We are seeking a highly skilled Research Scientist to contribute to our immunology/immuno-oncology research efforts at Medix ™ in Philadelphia, PA. The ideal candidate will have extensive experience in oncology and/or immunology drug discovery, as well as expertise in immunology assays (cytotoxicity, MSD, etc.).
Key Responsibilities:
Design and execute in vitro pharmacology assays to support functional validation of lead molecules. Generate scientific technical reports to support regulatory filings. The successful candidate will have a strong understanding of cancer biology and be able to analyze data independently, construct graphs in GraphPad/Prism or Excel, and present data/key findings in Microsoft Power Point format.
Required Skills & Experience:
Proficient in the following assays/techniques:
- Cell culture of tumor cell lines and T cells (PBMCs/PAN-T)
- Multi-color Flow cytometry/FACs to analyze tumor and/or T cell antigen surface expression, binding curves, receptor quantification
- T cell mediated cytotoxicity assays using Incucyte/Satorius and/or Cell Titer Glo assay systems
- MSD/Luminex for measuring cytokine production
- Familiar with FlowJo for FACs analysis
- Familiar with MSD analysis
- Mammalian cell culture
- Ability to analyze data independently and construct graphs in GraphPad/Prism or Excel
- Ability to present data/key findings in Microsoft Power Point format, construct slides in a clear coherent manner
- BS or MS in relevant biologic sciences or cell biology with 1-4 years prior laboratory experience in a drug discovery setting
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