Scientific Leader

ViiV Healthcare is seeking a highly skilled Scientific Leader to join our Discovery DMPK team in Branford, CT. As a key member of our team, you will be responsible for driving the DMPK strategy for multiple Drug Discovery stage projects from early lead optimization through Phase I clinical studies.

• Develop and implement DMPK strategies for assigned projects, ensuring translational PKPD approaches and appropriate screening cascades with multi-parametric optimization.
• Design and conduct bespoke mechanism-based studies to address program needs, utilizing your extensive laboratory experience.
• Efficiently manage your time and project requests for DMPK work to ensure optimal support of projects across different modalities in the ViiV Discovery pipeline.
• Coordinate and deliver high-quality DMPK written contributions to technical and regulatory documents.
• Develop and maintain excellent working relations with stakeholders in Discovery project teams, ensuring strategic alignment.
• Actively support cross-DMPK initiatives as a representative from the ViiV Nonclinical Safety and DMPK team to drive DMPK science and operations.

• MS Degree (7 years experience) or PhD (>2 years experience post graduation) in a field relevant to DMPK (e.g., Pharmacology, Biochemistry, Pharmacokinetics or Drug Metabolism).
• Experience state-of-the-art DMPK science in projects to enable the discovery of new medicines, including experience with small molecules and biologics drug discovery and/or development.
• Experience managing DMPK related project resources and budgets.
• Experience working in cross-matrix teams, with demonstrated experience in project milestone delivery.

• PhD in a field relevant to DMPK (e.g., Pharmacology, Biochemistry, Pharmacokinetics or Drug Metabolism) with >5 years drug discovery experience.
• In-depth experience in DMPK representation in Discovery projects across different modalities (e.g., small molecule, mAb, long-acting injectable) and has strong experience in human dose prediction.
• Examples demonstrating the successful selection of drug candidates through efficient ADME screening cascades such as multi-parametric optimization, translational PKPD and human dose optimization strategies.
• Experience in leveraging modeling approaches and predictive science in Discovery projects to accelerate timelines and increase probability of success.
• Excellent communication/written skills and collaboration as demonstrated through publication and/or external interactions (e.g., university collaborations, speaking invitations etc.).

Why ViiV Healthcare?

ViiV Healthcare is a pharmaceutical company solely focused on combating, preventing, and ultimately eradicating HIV and AIDS. We are guided by our mission to leave no person living with HIV behind and it is this mission that unites our employees located across the globe. We combine expertise in research, manufacturing, policy and more to push the boundaries of what people think is possible in HIV treatment and care.

At ViiV Healthcare, we are committed to diversity and inclusion, and we strive to create a workplace where everyone feels valued, respected, and empowered to contribute their best work. We believe that a diverse and inclusive workplace is essential to driving innovation and delivering exceptional results.

If you are passionate about making a difference in the lives of people living with HIV, we encourage you to apply for this exciting opportunity to join our team as a Scientific Leader - Discovery DMPK.