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Lead Scientist, Translational Research
2 months ago
PharmaEssentia U.S.A. is on the lookout for a dedicated and skilled Lead Scientist to enhance our Translational Research team. This role is pivotal in advancing the development of innovative biotherapeutics, including cytokines, antibodies, and antibody-drug conjugates.
The ideal candidate will be instrumental in the design, execution, and analysis of translational biomarker studies and mechanism of action (MOA) investigations, facilitating the transition of groundbreaking therapeutics from late-stage discovery into first-in-human clinical trials and beyond.
In this capacity, you will leverage your knowledge in pharmacokinetics, pharmacodynamics, and biomarker identification to steer drug development strategies, optimize dosing protocols, and ensure the safety and effectiveness of investigational therapies.
Additionally, you will engage in translational initiatives aimed at maximizing the potential of our marketed therapies, focusing on indication expansion, innovative combinations, and refining biomarker methodologies to guide patient selection and dosing strategies.
Company Overview:
At PharmaEssentia, we offer a unique opportunity to make a significant impact on patient lives while expanding your professional horizons.
As a rapidly growing biopharmaceutical innovator, we are committed to utilizing our extensive expertise and scientific principles to develop effective biologics for challenging diseases, particularly in hematology, oncology, and immunology.
Founded by a team of experienced executives and renowned scientists, we are listed on the Taiwan Stock Exchange and are broadening our global footprint with operations across multiple countries.
Our new research center is dedicated to building upon our innovation efforts, focusing on transformative advancements in therapeutic areas.
Key Responsibilities:
1. Study Design and Execution: Lead the design and implementation of translational studies in relevant animal models and human cellular systems to identify and validate biomarkers and explore drug candidate mechanisms of action.
2. Data Analysis and Interpretation: Oversee the analysis and reporting of pharmacology and translational biomarker data, providing scientific insights to enhance study outcomes.
3. Drug Development Strategy: Contribute to the formulation and execution of clinical pharmacology strategies to advance investigational drugs through all clinical development phases.
4. Regulatory Interaction: Collaborate with regulatory affairs to support the preparation and review of regulatory submissions, addressing inquiries and providing scientific justifications.
5. Scientific Leadership: Act as a subject matter expert in translational biomarkers and therapeutic mechanisms, mentoring junior scientists and contributing to scientific literature.
6. Cross-Functional Collaboration: Work closely with teams across data sciences, biologics, immunology, clinical development, and regulatory affairs to integrate insights into drug development strategies.
Qualifications:
• Ph.D. in oncology, immunology, pharmacology, or a related field.
• 3+ years (for Lead Scientist) or 8+ years (for Senior Scientist) of experience in the pharmaceutical or biotechnology sectors, with a proven record in translational sciences.
• Expertise in in vivo model design and biomarker discovery.
• Strong analytical skills and proficiency in pharmacokinetic/pharmacodynamic software.
• Excellent communication and presentation abilities.
• Demonstrated leadership skills, with a focus on mentoring and teamwork.
Conclusion:
As a Lead Scientist in Translational Research, you will play a crucial role in enhancing our understanding of drug pharmacology and contributing to the development of innovative therapies that address unmet medical needs.
Your scientific expertise and collaborative approach will be vital in advancing drug development programs and improving patient outcomes at PharmaEssentia.
