Pharmacometrician (Hybrid, IL Based) - Clinical Pharmacology Expert

1 week ago


Chicago, Illinois, United States AbbVie Full time
Job Title: Pharmacometrician (Hybrid, IL Based)Job Summary:

AbbVie is seeking a highly skilled Pharmacometrician to join our team in a hybrid role. As a Pharmacometrician, you will be responsible for conceiving and executing statistical and mathematical models that achieve projects, Clinical Pharmacology and Pharmacometrics goals. You will propose PK/PD modeling and simulation ideas and implement those efforts. Investigate, identify, develop, and optimize methods and techniques in the field of PK/PD modeling. Act as a lead pharmacometrician in your area of expertise and critically evaluate relevant Pharmacometric, PK/PD, Clinical Pharmacology and regulatory advances and integrate this knowledge into Clinical Pharmacology strategy for research or development programs.

Responsibilities:
  • Contribute to clinical development by supporting Phase 1-4 studies with data analysis, modeling and simulation evaluations to guide study design, and clinical pharmacology strategy.
  • Author regulatory documents including analysis plans, study reports, population PK reports, exposure-response analyses reports, common technical documents, white papers, and other similar documents.
  • Conduct data analyses including non-compartmental analyses, modeling and simulation, advanced analytics, as well as literature data analyses.
  • Participate and present at various departmental and cross-functional teams such as Clinical Pharmacology meetings, Journal club.
  • Collaborate with scientific support from other Clinical Pharmacology functional groups to provide a unified clinical pharmacology position to clinical, CMC and regulatory teams.
  • Author scientific publications and present at scientific conferences
Qualifications:
  • PhD with 0 years of experience in a relevant field, Master's Degree or equivalent education and typically 7+ years of experience, Bachelor's Degree or equivalent education and typically 10+ years of experience;(*relevant field includes experience with data science, mathematics, biostatistics, modeling and simulation, Pharmacometrics or systems pharmacology)
  • NONMEM and R experience preferred
  • Excellent interpersonal skills
  • Ability to interact externally and internally and perform in a team setting
  • Demonstrates scientific acumen and has technical skills to perform the role
  • Key Leadership Competencies:
    o Persistent and resilient finds the way to move good ideas forward
    o Uses mistakes, failure and reflection as vehicles for learning and improvement
    o Delivers business results while also positioning AbbVie for long-term success
    o Connects unrelated concepts, generates original or unique ideas
    o Influences colleagues to achieve cross-functional alignment


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