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Clinical-Scientific - Research Associate Research Associate
3 months ago
Job Description: Summary:
Seeking a highly motivated and enthusiastic Research Associate II who will be part of the Material Generation Team (MGT) within Client Oncology's Process Development group. Within the MGT, this role will be primarily responsible for supporting the Upstream cell culture operations in our pilot-scale lab (up to 250L) to generate protein materials needed for cross-functional developments as well as GLP toxicology studies. This role will be expected to independently execute cell culture process from harvest to final fill and to be cross trained in Downstream purification processes. This role will also partially support activities in the Purification Process Development lab (15-20%). This is an exciting opportunity to learn the entire monoclonal antibody (mAb) production process, to join a growing & dynamic team, and to significantly contribute to Client Oncology's mission.
Responsibilities:
• Support protein material generation activities, including both mammalian cell culture and purification operations, from cell thaw to final formulated mAb.
• Escalate equipment or process issues as necessary. Help in troubleshooting and derivation of appropriate corrective action and resolution.
• Prepare buffer and media solutions to support material generation and process development runs.
• Perform equipment (e.g., bioreactor, purification skid, pH meters, and chromatography column, etc.) maintenance.
• Maintain accurate and detailed records of all lab activities and work routinely with electronic data records and applications.
• Generate technical reports and present them in internal meetings.
• Purchase raw materials and consumables.
Qualifications:
• Hands-on cell culture experience includes operating both bench-top glass vessel, large-scale single-use bioreactor systems, and associated activities.
• Able to follow lab operating procedures and safety guidelines.
• Detail oriented with strong organization and time management skills.
• Team player, motivated and willing to learn and grow.
• Effective written and verbal communication skills.
• Familiarity with lab software and/or electronic lab notebooks (ELN).
• Able to lift and move 50 lbs. repeatedly.
• Weekend and holiday work is required when needed.
Preferred Qualifications:
• Familiar with purification process and operations.
• Proficient in lab automation.
• Proficiency with ELN and data management (Benchling).
• Biomanufacturing experience.
Must Have:
1. Able to lift and move 50 lbs. repeatedly.
2. Weekend and holiday work is required when needed.
3. Able to follow lab operating procedures and safety guidelines.
1. Mammalian cell culture (Pilot)
2. Buffer and Media Prep
3. Lab Eq Maintenace
Interview Process:
1st Virtual Team (camera on)
2nd On-site
Position Comments visible to Supplier: Location is Bothell, WA
100% on-site
Request: Clinical-Scientific - Research Associate
Number of Contractors Needed: 1
Candidate Submission Limit Per Supplier: 2
Desired Start Date: 7/22/2024
Hrs/Wk: 40.00
MSP Owner: Brock, Heather
