Scientific Director, Precision Medicine Immunology- Head of Gastroenterology or Rheumatology

1 week ago

Worcester, United States CareerBuilder Full time

Company Description
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
Job Description
The Precision Medicine Department at Abbvie is committed to advancing drug development and patient care through building a deeper understanding of disease biology and developing tools to optimize clinical decision making and customize treatment for individual patients. Abbvie is seeking a highly motivated and experienced translational scientist to lead a team of senior scientists accountable for driving the development, planning, and execution of the clinical translational research and precision medicine strategy across the rheumatology or gastroenterology drug pipeline at Abbvie.
Key Responsibilities:
* Build and lead an internal team of highly experienced and accomplished translational scientists (Precision Medicine Leads) accountable for defining and implementing the translational research and precision medicine strategy in for disease areas (RA, PsA, SLE, etc..) and assets being developed for rheumatology or gastroenterology(Crohn's disease and ulcerative colitis). Responsibilities extend from Lead Optimization in Discovery through mature product life cycle in Development:
* Define translational research strategy in rheumatology or gastroenterology to support clinical success of pipeline assets, including PD/TE biomarkers, POM biomarkers, patient selection/stratification strategies, and development of novel disease biomarkers.
* Manage the design, conduct, interpretation and reporting of biomarker data/activities for pipeline assets in line with the development, regulatory and commercial strategies
* Lead asset-specific translational projects/teams in a matrix environment.
* Coordinates appropriate scientific and medical activities with internal stakeholders (i.e. commercial, clinical operations, discovery, statistics, regulatory, etc.) to execute high quality biomarker strategies in the clinic.
* Ensure, in collaboration with project leaders and asset-specific translational team members, that clinical translational sciences budgets, timelines, publication strategies and regulatory compliance requirements are factored into programs' scientific activities.
* Serve as Precision Medicine Lead for one or more assets within the Immunology pipeline
* Provide subject matter expertise on cross-functional teams defining broader corporate strategy in rheumatology or gastroenterology.
* Initiate new areas of investigation and implement cutting-edge technologies that are scientifically meaningful, reliable and can be incorporated directly into a clinical development program.
* Develop productive collaborations with key stakeholders within Abbvie such as Discovery Immunology, CDx, Clinical Development, etc
* Establish external network and build collaborations that complement internal efforts to advance mechanistic understanding of therapeutics and inform development opportunities.
* Prepare and present summaries of translational data for discussions with key stake holders across multiple functional areas.
Significant Work Activities -Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Qualifications
* PhD and typically 15+ years of experience, Master's Degree or equivalent education and typically 20+ years of experience, Bachelor's Degree or equivalent education and typically 25+ years of experience in academia or industry.
* Strong scientific background in immunology, rheumatology or related field supported by publication record in these areas.
* Expertise in one or more rheumatological diseases or inflammatory bowel disease is highly desirable.
* Knowledge of clinical trial methodology, regulatory requirements governing clinical trials, companion diagnostics/in vitro diagnostics, protocol design, and/or experience in development strategy preferred.
* Demonstrated leadership in translational sciences (employing pharmacodynamic, predictive and exploratory biomarkers) and experience with development of assays including ligand binding assays, IHC/IF, gene expression profiling, flow cytometry.
* Ability to manage clinical translational programs and teams with moderate supervision.
* Demonstrate creative 'out of the box' thinking to solve difficult problems.
* Organization, detail oriented, and effective time management with an ability to adapt to changing priorities.
* Familiarity with data management and visualization tools and collaborating with computational biology to analyze complex data sets emerging from clinical trials.
* Excellent written and oral communication skills, ability to present the results in clear and concise manner.
* Strong interpersonal, influencing and collaboration skills to work in a team-oriented, matrix environment, and the ability to work through conflicts.
* Experience managing senior level scientists (PhD/MS) is a plus.
Key Leadership Competencies:
* Builds strong relationships with peers and cross functionally with partners to enable high performance.
* Inspires others to lead and have a "can-do" attitude to overcome challenges
* Learns fast, grasps difficult concepts, and can change course quickly where indicated.
* Strong communication and teamwork skills are essential as the candidate is expected to interact with diverse groups within Abbvie and through external collaborations.
* Raises the bar and is never satisfied with the status quo.
* Creates a learning environment, is open to suggestions and experimentation for improvement.
* Embraces the ideas of others, nurtures innovation and manages innovation to reality.
* Strong interpersonal and communication skills with demonstrated ability to work within a team environment.
Additional Information:
* Travel: 10%
* Job Type: Experienced
* Schedule: Full-time
Additional Information
Applicable only to applicants

#J-18808-Ljbffr

  • Project Director II, Immunology

    Found in: Resume Library US A2 - 1 week ago

    Worcester, Massachusetts, United States AbbVie Full time

    Job Description Primary responsibility is to advance multiple research projects from Lead Optimization through Candidate Selection stages through effective leadership of matrixed, multi-disciplinary teams with membership from discovery, precision medicine, preclinical safety and safety pharmacology, DMPK-BA, CMC, clinical development, and others. Programs...

  • Full Time Family Medicine Physician

    Found in: beBee jobs US - 1 week ago

    Worcester, Massachusetts, United States BAS Healthcare Full time

    Location: A safe and friendly family-oriented community that offers lots of outdoor recreation and is only 60 miles to Boston and 30 miles to Worcester, the state's second largest city. Access to affordable cost of living, great private and public schools, golfing, skiing, and hiking. Facility: Non-profit physician organization affiliated with local area...

  • Full Time Family Medicine Physician

    Found in: beBee S US - 2 weeks ago

    Worcester County, United States BAS Healthcare Full time

    Location: A safe and friendly family-oriented community that offers lots of outdoor recreation and is only 60 miles to Boston and 30 miles to Worcester, the state’s second largest city. Access to affordable cost of living, great private and public schools, golfing, skiing, and hiking. Facility: Non-profit physician organization affiliated with local...

  • Assistant/Associate/Full Professor, Tenure Track

    Found in: beBee jobs US - 3 weeks ago

    Worcester, Massachusetts, United States UMass Chan Medical School, Department of Medicine, Division of Innate Immunity Full time

    The Division of Innate Immunity and the Department of Medicine at the University of Massachusetts Chan Medical School invite applications for a Tenure-track faculty position at the Assistant, Associate, or Full Professor Level. Rank will be commensurate with ability and experience. The position will be highly competitive with regard to start-up funds,...

  • Full Time Obstetrics and Gynecology Physician

    Found in: beBee jobs US - 1 week ago

    Worcester, Massachusetts, United States BAS Healthcare Full time

    Location: A safe and friendly family-oriented community that offers lots of outdoor recreation and is only 60 miles to Boston and 30 miles to Worcester, the state's second largest city. Access to affordable cost of living, great private and public schools, golfing, skiing, and hiking. Facility: Non-profit physician organization affiliated with local area...

  • EPSIP- Scientific Marketing, Web Design, and Communication Intern

    1 week ago

    Worcester, United States University of Massachusetts Medical School Full time

    Overview: **IMPORTANT: Your application will not be considered without an essay** Complete the online application and include a short essay either in the "resume" field (the resume and essay should be uploaded as one document) or uploaded as a cover letter on your profile. Essay topic is listed below (Please include within your essay, examples from personal...

  • Full Time Obstetrics and Gynecology Physician

    Found in: beBee S US - 2 weeks ago

    Worcester County, United States BAS Healthcare Full time

    Location: A safe and friendly family-oriented community that offers lots of outdoor recreation and is only 60 miles to Boston and 30 miles to Worcester, the state’s second largest city. Access to affordable cost of living, great private and public schools, golfing, skiing, and hiking. Facility: Non-profit physician organization affiliated with local...

  • EPSIP- Scientific Marketing, Web Design, and Communication Intern

    Found in: Resume Library US A2 - 1 week ago

    Worcester, Massachusetts, United States University of Massachusetts Medical School Full time

    Overview: IMPORTANT: Your application will not be considered without an essay   Complete the online application and include a short essay either in the "resume" field (the resume and essay should be uploaded as one document) or uploaded as a cover letter on your profile. Essay topic is listed below (Please include within your essay, examples from...

  • Post Doctoral Associate

    5 hours ago

    Worcester, United States University of Massachusetts Medical School Full time

    Overview We are inviting applications for postdoctoral positions to pursue multiple research topics that encompass: gene therapy using AAV vectors, RNA therapy, gene editing, immunology, virology, and AAV vector development. Applicants should have a PhD degree or an MD with post-graduate scientific training, and at least three years of research experience...

  • EPSIP- Scientific Marketing, Web Design, and Communication Intern

    Found in: Talent US A C2 - 7 hours ago

    Worcester, United States InsideHigherEd Full time

    Overview**IMPORTANT: Your application will not be considered without an essay** Complete the online application and include a short essay either in the "resume" field (the resume and essay should be uploaded as one document) or uploaded as a cover letter on your profile. Essay topic is listed below (Please include within your essay, examples from...

  • Post Doctoral Associate

    7 hours ago

    Worcester, United States University of Massachusetts Medical School Full time

    We are inviting applications for postdoctoral positions to pursue multiple research topics that encompass: gene therapy using AAV vectors, RNA therapy, gene editing, immunology, virology, and AAV vector development.  Applicants should have a PhD degree or an MD with post-graduate scientific training, and at least three years of research experience in...

  • Head Girls' Varsity Soccer Coach

    Found in: beBee jobs US - 17 hours ago

    Worcester, Massachusetts, United States Bancroft School Full time

    Bancroft School in Worcester, MA is seeking a Head Girls' Varsity Soccer Coach to begin in the fall of 2024. The competitive season runs from late August through the second or third week in November. The Head Girls' Varsity Soccer Coach position bears important responsibilities that include acting as a role model supporting the mission of the school, and...

  • Research Associate I

    8 hours ago

    Worcester, United States University of Massachusetts Medical School Full time

    Overview POSITION SUMMARY: The Department of Pathology at UMass Chan Medical School located in Worcester, Massachusetts, invites applications for Research positions at the Research Technician or Research Associate level. We are seeking individuals with a BA/BS in a Biological/Life Sciences. The ideal candidate would have a background in Immunology,...

  • Principal Research Scientist I

    7 hours ago

    Worcester, United States AbbVie, Inc Full time

    Company Description AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services...

  • Accounts Payable Specialist

    2 weeks ago

    Worcester, United States PI (Physik Instrumente) LP, Full time

    Job DescriptionJob DescriptionPI (Physik Instrumente), LP is the world leader in high precision positioning systems: Nano Positioning, Micro Positioning, Precision Motion and Automation Systems. Our product lines include piezoelectric-based nano-positioners, motorized stepper and servo stages, and linear motor stages. Our customers are the leading OEM’s...

  • Experienced Admissions Director

    1 week ago

    Worcester, United States Bear Mountain Healthcare Full time

    Bear Mountain Healthcare - Bear Mountain at Worcester is looking for an experienced Admissions Director for their two speciality programs- NeuroBehavioral Programming and SubAcute Ventillator/Trach/Respiratory Programming. The ideal candidate will have prior clinical and financial screening experience and be able to qualify referrals for admission. This...

  • Research Associate

    4 hours ago

    Worcester, United States University of Massachusetts Medical School Full time

    Overview POSITION SUMMARY: The Department of Pathology at UMass Chan Medical School located in Worcester, Massachusetts, invites applications for Research positions at the Research Technician or Research Associate IV level. We are seeking individuals with a BA/BS in a Biological/Life Sciences. The ideal candidate would have a background in Immunology,...

  • Experienced Admissions Director

    6 days ago

    Worcester, United States Bearmountainhc Full time

    Bear Mountain at Worcester is looking for an experienced Admissions Director for their two speciality programs- NeuroBehavioral Programming and SubAcute Ventillator/Trach/Respiratory Programming. The ideal candidate will have prior clinical and financial screening experience and be able to qualify referrals for admission. This position will be responsible...

  • Research Associate I

    Found in: Talent US A C2 - 22 hours ago

    Worcester, United States InsideHigherEd Full time

    OverviewPOSITION SUMMARY:  The Department of Pathology at UMass Chan Medical School located in Worcester, Massachusetts, invites applications for Research positions at the Research Technician or Research Associate level. We are seeking individuals with a BA/BS in a Biological/Life Sciences. The ideal candidate would have a background in Immunology,...

  • Research Project Director

    22 hours ago

    Worcester, United States University of Massachusetts Medical School Full time

    Overview: GENERAL SUMMARY OF POSITION: Under the general direction of the Principal Investigator or designee, the Research Project Director is responsible for coordinating the daily operations of child health equity-focused research studies. This position will be primarily overseeing a new multi-site NIH-funded R01 focused on applying an antiracism lens to...