Director of Platform Informatics

2 months ago


Birmingham, United States Southern Research Institute Full time
Director of Platform Informatics

General Summary

Southern Research (SR) is at a pivotal moment in its 82-year history. At the start of 2022, SR launched a new strategic plan focused on translational research in the life sciences. SR intends to invest over $150 million in this new strategy, including development of new facilities, platforms, and programs. We believe in the power of SR and our partners to unlock the immense potential of Alabama's biotech ecosystem to spur economic development, create jobs, and draw investment. Downtown Birmingham sees over $700M in extramural biomedical research every year, including over $300M from the NIH, in large part due to the contributions of Southern Research and the University of Alabama at Birmingham. We are on a mission to translate our R&D volume into investment, high-performance companies, and quality jobs in Alabama and in the Southeast United States.

The Director of Platform Informatics will report to the Chief Data Officer. The Director of Platform Informatics will be a technical leader whose team is responsible for creating and maintaining a clinicogenomic datalake along with the ETL processes for genomic sequencing results and interpretations, and clinical data mapping and translation from HL7 FHIR to OMOP standards. In this role, you will focus on accelerating precision medicine through facilitating clinicogenomic data applications and building of an integrated research workbench framework for data querying, cohort building, clinical trial matching, biomarker discovery, therapeutic lead generation, and additional analytics and result visualization. You will work internally with other Data Teams in Bioinformatics and Quality Control, as well as, externally with biopharmaceutical sponsors and academic research collaborators providing an interactive and data-driven view into clinicogenoimc determinants of health and disease.

Key Responsibilities
  • Architect, implement and maintain healthcare data interoperability strategies, integrating metadata and clinical data from Laboratory Information Systems (LIS) and various Electronic Health Record (HER) / Electronic Medical Record (EMR) / Health Information Exchange (HIE) networks.
  • Manage workflow design, building and testing of interfaces, and support production solutions'
  • Creation and expansion of a viable, reliable, reusable, extensible platform that enables analysis and exploration of clinicogenomic data as well as reporting capabilities for providers and patients.
  • Work directly with external customers as well as IT vendors on the development of system interfaces including writing detailed interface specifications that describe how the interface will work.
  • Communicate, coordinate and escalate interface issues to seek timely resolution and ensures communications are clear and effective with internal and external team members, vendors and key stakeholders
Minimum Qualifications
  • Ph.D. in Bioinformatics, Computational Biology, Biostatistics, Statistics, Computational Epidemiology, Biophysics, Physics, Biological Computational Sciences or a related field.
  • 10+ years of experience in building and supporting large clinicogenomic datasets for research applications and analytic framework integrations.
  • Extensive experience with AWS cloud computing infrastructure for Platform Informatics workflows and analytic frameworks.
  • Extensive experience with cloud datalake and database infrastructures (Snowflake preferred); additional experience with access-controlled platform hosting of clinicogenomic data sets for data querying and hypothesis generation by research collaborators a strong plus.
  • Ability to read or certified to read clinical records and Electronic Health Records.
ABOUT SOUTHERN RESEARCH

Southern Research (SR) represents a bold vision for an enduring industry-university partnership that advances research and discovery in life sciences and engineering. As we celebrate our 80 th anniversary, we are making transformational decisions to reinvigorate the institute by focusing our efforts to attract, retain, and develop top talent, and ultimately create jobs through translating ideas into innovation, and innovation into economic opportunity.

Job Specifics Behaviors

Strategic Decisionmaker - Obtains information and identifies key issues relevant to achieving a long-range goal; commits to a course of action after developing alternatives based on logical assumptions, facts, constraints, and resources.

Strategic Relationship Builder - Uses appropriate interpersonal styles to work effectively with others to meet mutual goals and objectives; understands the role & interrelationships of each organizational function; possesses skill in managing across functional and organizational lines.

Mission and Community Driven - Has an authentic desire to help steward Southern Research's culture, guard of our values, and champion our mission of innovation-driven economic development through translation of excellent scientific research.

Impactful Communicator - Expresses thoughts and ideas effectively in individual and group situations; adjusts language to the needs of the audience.

Results Oriented - Establishes stretch goals and manages to focus outcomes; demands excellence and demonstrates a strong commitment to organizational success; works to do what is best for all stakeholders.

Coaches / Develops Others - Uses appropriate interpersonal style to guide direct reports to action, create a sense of ownership, and encourage individuals to stretch beyond their own capabilities.

Inclusive - Holds a strong conviction that inclusion and innovation go together.

Highly collaborative - Cares less about who did it than how it got done; takes pride in shared outcomes and believes the whole is greater than the sum of the parts when it comes to team efforts.

Deeply curious - Recognizes that "innovation requires not knowing long enough to learn new things" and that "being actively open-minded involves searching for reasons why we might be wrong-not for reasons why we must be right-and revising our views based on what we learn."

Action oriented - Translates goals and objectives into actionable, metrics focused priorities and work streams for the team to execute.

Process Refiner - Observes details to continuously improve processes, looks for opportunities to create regular feedback loops to refine, and loves measuring what matters; strongly believes that "getting it right is more important than being right."

Core Values

Cultivating human connection - putting people first. We know that every individual makes a difference and that no one can do it alone. We believe the world's most powerful resource is human potential. We are an inclusive and courageous team where innovation and diversity of though go hand in hand. We understand that relationships move at the speed of trust.

Operating with precise execution - measuring what matters and owning results as a team. We leverage data to drive decisions that advance science. We recognize the importance of a stable foundation coupled with an agile mindset. We hold ourselves accountable and take pride in our work. We give and receive candid feedback as a gift that keeps us growing.

Harnessing relentless curiosity - our unstoppable, innovative force. We are driven to ask sharp questions and push the boundaries of knowledge. We use creativity and critical thinking as catalysts for finding solutions that change lives. We learn by doing, consistently striving to improve our relationships, training, methodologies, questions, and results.

Stewarding a healthy community - implementing sustainable operations for a safe, engaging environment. We don't compromise on safety and health for our employees, customers, or community. We believe a healthy community begins with inclusive economic opportunities. We respect the dignity of the patients we ultimately serve. We are motivated to serve communities that are underserved and markets that are overlooked.

Physical Demands
  • Ability to work in an office setting using a computer for extended periods of time.
  • Ability to sit for extended periods of time.
  • Some travel required.


  • Birmingham, United States Southern Research Full time

    Director of Platform Informatics  General Summary Southern Research (SR) is at a pivotal moment in its 82-year history. At the start of 2022, SR launched a new strategic plan focused on translational research in the life sciences. SR intends to invest over $150 million in this new strategy, including development of new facilities, platforms, and programs....


  • Birmingham, United States Southern Research Full time

    Director of Platform Informatics  General Summary Southern Research (SR) is at a pivotal moment in its 82-year history. At the start of 2022, SR launched a new strategic plan focused on translational research in the life sciences. SR intends to invest over $150 million in this new strategy, including development of new facilities, platforms, and programs....


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