Group Leader, Metabolism
4 weeks ago
Company info
NewLimit is a biotechnology company working to radically extend human healthspan. Were developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.
Description
NewLimit is seeking a liver biologist with leadership experience to join our Metabolism team. Our Metabolism team is developing reprogramming medicines to restore youthful function in aged hepatocytes in the context of metabolic disease.
In this role, you will develop and perform assays for hepatocyte function, contribute to team decision making, and serve as a subject matter expert within NewLimit to enable our therapeutic development efforts.
As the leader of the Metabolism team, you will:
Lead a team of Scientists and Research Associates to develop epigenetic reprogramming therapies while remaining involved in day-to-day execution
Collaborate with our Single Cell Technology, Epigenetic Editing, and Predictive Modeling teams to design, build, and test epigenetic reprogramming interventions for aged and diseased hepatocytes
Contribute to NewLimits product development decisions, company-wide goals, and technology platform
Serve as a company-wide expert on metabolic diseases and liver biology
Develop assays to measure hepatocyte function both
ex vivo
and
in vivo
Evaluate epigenetic reprogramming payloads using
ex vivo
and
in vivo
functional assays to select therapeutic candidates
Requirements
Ph.D. in cell biology, molecular biology, biochemistry or a related field or equivalent industry experience (5+ years)
Experience leading a cross-functional team and managing direct reports
Experience with therapeutic development, as demonstrated through contributions to a pre-clinical or clinical stage program
Experience designing and executing experiments in animal models of liver dysfunction
Deep knowledge of metabolic disease, liver biology, and relevant therapeutic modalities
Nice to have
Experience with
in vivo
nucleic acid delivery technologies (e.g. viral vectors, endosomes, lipid nanoparticles)
Experience with bulk and single cell functional genomics methods
Experience with iterative product development cycles (e.g. design-build-test-learn)
Benefits
NewLimit offers generous benefits to ensure our team can focus on our mission:
Health, dental, and vision insurance
401(k) with company match
Paid parental leave
Industry-leading paid time off (PTO) 20 days/year for all employees + holidays
Meals and snacks on-site
#J-18808-Ljbffr
-
Vice President, Medical Group Operations
3 weeks ago
San Francisco, United States Sutter West Bay Medical Group Full timePOSITION SUMMARYHealthcare Administrative leader for a San Francisco based multi-specialty medical group that provides primary through quaternary care in both ambulatory and hospital settings. The ideal candidate for this role will possess a strong operational background gained from experience within a health system, and an appreciation of medical group...
-
Vice President, Medical Group Operations
3 weeks ago
San Francisco, California, United States Sutter West Bay Medical Group Full timePOSITION SUMMARYHealthcare Administrative leader for a San Francisco based multi-specialty medical group that provides primary through quaternary care in both ambulatory and hospital settings. The ideal candidate for this role will possess a strong operational background gained from experience within a health system, and an appreciation of medical group...
-
Research Nurse I
3 weeks ago
South Pasadena, United States CEDARS-SINAI Full timeJob Description Do you have a passion for the highest quality and patient happiness? Cedars-Sinai is an international leader in biomedical research, we translate discoveries into successful treatments with global impact. The Research Nurse I will provide hands-on treatment, monitoring and follow-up clinical analysis of patients participating in clinical...
-
Director, Clinical Program Management
1 month ago
South San Francisco, United States Meet Full timeDirector of Clinical Program ManagementHybrid in South San Francisco, CAMeet has partnered with a local biotech leading in cutting-edge treatments in the cardiometabolic space. Our client has a strong pipeline that has garnered extensive attention from investors following promising clinical data. They are looking for an experienced Program Manager to join...
-
Director, Clinical Program Management
5 days ago
South San Francisco, United States Meet Full timeDirector of Clinical Program ManagementHybrid in South San Francisco, CAMeet has partnered with a local biotech leading in cutting-edge treatments in the cardiometabolic space. Our client has a strong pipeline that has garnered extensive attention from investors following promising clinical data. They are looking for an experienced Program Manager to join...
-
Senior Director, DMPK
1 month ago
San Diego, California, United States Vertex Pharmaceuticals, Inc Full timeVertex San Diego Drug Metabolism and Pharmacokinetics (DMPK) team is seeking a highly motivated, experienced scientist and leader Senior Director level to help advance discovery and development of transformational therapies for serious unmet medical needs.The Senior Director of Drug Metabolism & Pharmacokinetics will be part of the global DMPK and local site...
-
Medical Director
2 days ago
South San Francisco, United States Third Rock Company Full time**Medical Director / Senior Medical Director, APOL1 Project Team Leader** at **Maze Therapeutics** We Are Genetic Navigators bringing together passionate, creative and dedicated professionals to join a rapidly growing biotech in our mission to translate novel genetic insights into lifesaving medicines. We are seeking an experienced Director/Senior Medical...
-
Medical Director
1 day ago
South San Francisco, United States Mazetx Full time**Medical Director / Senior Medical Director, APOL1 Project Team Leader** at Maze Therapeutics South San Francisco **We Are Genetic Navigators** bringing together passionate, creative and dedicated professionals to join a rapidly growing biotech in our mission to translate novel genetic insights into lifesaving medicines. **We are seeking** an experienced...
-
Senior Sales/Business Development Leader
2 days ago
San Francisco, United States Aledium Group Full timeJoin Our Client as a BizDev Leader in the Heart of California's Tech Scene!Location: Bay Area, CaliforniaGet Ready to Innovate The Aledium Group is a sister company of AlediumHR. We specialize in business development roles, primarily within the information technology sector. We are actively recruiting for a fantastic Israeli hardware company that's pushing...
-
Director, DMPK
1 month ago
San Francisco, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Director, DMPK
4 weeks ago
San Francisco, California, United States Eli Lilly and Company Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...
-
Senior Counsel, Research
1 month ago
South San Francisco, United States Roche Full timeThe PositionThe Genentech R&D Law Group is seeking a highly experienced R&D attorney. As a partner and key business strategist, this individual will have deep experience in regulatory law and complex transactional legal support for global strategies and activities related to product research and development, digital health and personalized healthcare. As a...
-
GROUP LEADER-A&G
4 days ago
San Antonio, United States SWRI Full timeResponsible for smooth and efficient day-to-day operation of the group, including but not limited to assign requisitions, answer questions, provide guidance, resolve issues and place orders. As the leader of the group, have regular meetings with staff, internal end users/divisions to set priorities, expectations, and advise/educate on purchasing policies...
-
Market Leader Trainee
1 month ago
San Francisco, United States 7-Eleven Full timeAre you looking for an exciting fast-paced work environment where you will typically lead a group of 8-10 Area Leaders with responsibility for approximately 100 - 150 stores? The Market Leader assists and counsels Area Leaders and Store Operators (store managers and franchisees) in the daily operations of their stores with a goal to maximize sales and gross...
-
Market Leader Trainee
2 weeks ago
San Francisco, United States 7-Eleven Full timeAre you looking for an exciting fast-paced work environment where you will typically lead a group of 8-10 Area Leaders with responsibility for approximately 100 – 150 stores? The Market Leader assists and counsels Area Leaders and Store Operators (store managers and franchisees) in the daily operations of their stores with a goal to maximize sales and...
-
Group Product Manager
7 days ago
San Francisco, United States Hevo Data Full timeGroup Product Manager, Hevo, US We are looking for an exceptional product management leader to join our team at Hevo. You will have a deep understanding of the data integration (ELT/ETL) space. Working cross-functionally, you will align the product management, product marketing, sales, sales engineering, and partner ecosystem to deliver solutions for...
-
Associate Director, Clinical Science
4 weeks ago
South San Francisco, United States Maze Therapeutics Full timeThe Position: At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for an Associate Director, Clinical Science to join our Clinical Science team and take a central role in pioneering the future of...
-
Jack In The Box
2 days ago
South Jordan, United States Seasons Restaurant Group Full timeCompensation: $15.00 - $18.00/ hour Jack in the Box Team Leader Craving career satisfaction? Bring home the bacon and put a burger on it. As the Team Leader, you will be empowered to act as the first-line operational supervisor responsible for training and leading team members in providing a great guest experience. You will create an...
-
Associate Director, Clinical Science
3 weeks ago
South San Francisco, United States Maze Therapeutics Full timeThe Position: At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for an Associate Director, Clinical Science to join our Clinical Science team and take a central role in pioneering the future of...
-
Advisor - Dmpk
1 hour ago
San Francisco, United States Lilly Full timeAt Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...