Biologist (Ddpcr/cho Cell Line

2 weeks ago

Worcester, United States Infobahn Softworld Inc Full time

**About the Job**

The Bioprocess Development and Launch Department at the Bioresearch Center in Worcester, MA is seeking a highly motivated molecular biologist to join the CHO Cell Line Development team and advance the Biologics pipeline.

**The scientist in this position will**
- Have several responsibilities in supporting CHO biologics pipeline, including genetic characterization of cell lines and cell banks.

**Key Responsibilities**:

- Characterize CHO cell lines using molecular biology techniques, including qPCR, ddPCR, Southern blot, and northern blot
- Sanger sequencing analysis
- Design of primer/probe reagents for gene copy number analysis
- Use of gel and blot imaging instruments
- Maintain detailed, accurate, and clear documentation of experiments and activities
- Effectively organize and communicate research progress and planned activities through oral and written presentations
- Collaborate with colleagues in the Cell Line Development group and across multiple functional areas of the Bioprocess Development and Launch department to advance the company Biologics Pipeline
- Maintain a high level of productivity in the lab
- Demonstrate scientific initiative and creative thinking to achieve project goals and contribute team performance in a climate of scientific rigor
- Contribute to the smooth and effective operation of the CHO Cell Line Development labs through the 5S program
- Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, and GxP compliance

**Qualifications**:

- Bachelor’s Degree or Master’s Degree in Cell/Molecular Biology or a related field with 5 years of relevant experience; pharmaceutical industry experience is preferred
- Expertise in molecular biology techniques, including DNA/RNA extraction and quantification, PCR-based assays, gel electrophoresis, blotting techniques and sequencing analysis
- Hands-on experience with mammalian cell culture
- Experience with DNA sequence manipulation software and common software packages such as Microsoft Office
- Excellent written and interpersonal communication skills with the ability to build strong relationships with peers and cross-functional team members
- Strong planning, multitasking, time management, and troubleshooting skills
- Collaborative and proactive attitude with strong scientific curiosity, work ethic, and attention to detail
- Authorization to work in the United States is required

**Preferred Qualifications**:

- Experience with expression vector elements, construction, and molecular cloning
- Experience with digital PCR assays, such as droplet digital PCR (ddPCR)
- Proven track record in vector biology, cell line genetic characterization, and/or CHO cell line development

**What are the top 3-5 skills, experience or education required for this position?**
- Experience with expression vector elements, construction, and molecular cloning
- Experience with digital PCR assays, such as droplet digital PCR (ddPCR)
- Proven track record in vector biology, cell line genetic characterization, and/or CHO cell line development

**Job Types**: Full-time, Contract

Pay: $50.00 - $51.00 per hour

Schedule:

- 8 hour shift
- Day shift
- Monday to Friday

**Education**:

- Bachelor's (preferred)

**Experience**:

- ddPCR: 5 years (preferred)
- expression vector elements and molecular cloning: 3 years (preferred)
- CHO cell cline development: 5 years (preferred)
- digital PCR assays, such as droplet digital PCR (ddPCR): 5 years (preferred)
- molecular cloning: 5 years (preferred)

Ability to Commute:

- Worcester, MA 01601 (required)

Work Location: In person

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