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Vice President, Clinical Development, Cardiovascular
4 months ago
**Job Title**:
Vice President, Clinical Development, Cardiovascular
**Location**:
San Diego, CA / Hybrid / Remote
**Position type**:
**FLSA**:
Full time- Exempt**Department**:
Clinical Development
**Strive to Bring a** Profound Difference to our Patients**:
At Avidity Biosciences, we are passionate about the impact of every employee in realizing our vision of improving people’s lives by delivering a new class of RNA therapeutics. Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. If you are a committed, solution-oriented thinker, join us in making a difference and become part of our growing culture that is integrated, collaborative, agile and focused on the needs of patients.
**The Opportunity**
**What You Will Contribute**
- Assist the CV translational research and discovery team with identifying appropriate clinical populations for pipeline assets and the design of translational studies to refine proof of concept hypotheses
- Support the development of regulatory strategies for cardiovascular development programs; identify and communicate potential risks
- Develop strong cross-functional working relationships with a diverse team of senior leaders
- Create, develop, and implement a successful therapeutic area strategy that will bring forth programs to successful approval and registration
- Provide strategic leadership and oversight for all aspects of clinical development activities primarily in the field of cardiology but may also provide leadership for neuromuscular assets
- Design and implement comprehensive clinical development plans in alignment with corporate goals and regulatory requirements
- Lead cross-functional teams to execute clinical trials, ensuring adherence to timelines, budgets, and quality standards
- Collaborate closely with internal stakeholders, including R&D, regulatory affairs, and medical affairs, to integrate clinical development strategies into overall product development plans
- Establish strong relationships with key opinion leaders, investigators, and clinical research organizations to support trial execution and patient recruitment efforts
- Drive the analysis and interpretation of clinical trial data, contributing to regulatory submissions, publications, and presentations
- Stay abreast of advancements in cardiology and cardiovascular medicine, providing insights into emerging trends and competitive landscapes
**What We Seek**
- Medical degree required; cardiovascular expertise preferential
- Minimum of 10 years of experience in clinical development within the biopharmaceutical industry, with a focus on cardiology; experience in genetic cardiomyopathies preferred
- Proven track record of successfully leading clinical development programs including rare indications from Phase I-III and regulatory approval
- Deep understanding of clinical trial design, execution, and regulatory requirements, particularly in cardiovascular therapeutic and rare disease areas
- Management experience, including managing direct reports, building teams, and leveraging relationships with clinical and commercial teams
- Experience leading a portfolio of programs at different clinical stages and with demonstrated ability to collaborate with both commercial and research
- Broad working knowledge of industry compliance requirements in USA and EU, clinical trial design and strategies, and medical information process
- Strong leadership skills with ability to inspire and motivate cross-functional teams to achieve ambitious goals
- Strategic thinker with keen analytical mindset and ability to translate complex data into actionable insights
- Demonstrated ability to thrive in a fast-paced, dynamic environment, adapting to evolving priorities and challenges
- Excellent written, communication, presentation and interpersonal skills, with the ability to effectively engage with internal and external stakeholders
- Ability to work collaboratively at all levels in a matrixed team environment
- A self-starter with hands-on approach to performing duties and excellent attention to detail
**Benefits of the Opportunity**
- Great management team who are all very experienced in developing and commercializing drugs
- Platform is first-in-class technology of antibody-oligonucleotide conjugates - able to effectively deliver oligonucleotides to tissues other than the liver, which has not previously been possible
- Already shown proof-of-mechanism with lead program in myotonic dystrophy type 1 - showed dose dependent delivery to muscle, improvement in the RNA splicing biomarkers and directional improvements in myotonia, muscle strength, and mobility
- Two other rare muscle disease programs in clinic (FSHD and DMD44) and rare cardiac targets heading towards IND
- Very well capitalized
***:
**What We
