Executive Director

**Working with Us**
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Title: Executive Director, Multiple Myeloma Disease Head

Translational Medicine at BMS Translational Medicine is part of the Global Research and Early Development organization in BMS and leads early stage clinical, pharmacological and translational research and development activities for the pipeline and supports late stage portfolio for regulatory, translational development and life cycle management. The Heme Translational Medicine Disease Team (TMDT) is a late translational group that supports multiple disease areas of interest including Myeloma, Myeloid, Lymphoma, Erythroid disorders, and other hematological malignancies. This group integrates scientific and business insights of multiple functions and leads the development of translational strategies at the franchise level and implements them in project teams to maximize the potential of BMS drugs.

Summary:
Reporting to the VP, Hematology Translational Medicine, the incumbent will be part of the translational group based in Summit NJ and will help develop translational disease and asset strategies in Multiple Myeloma or Myeloid/Erythroid disease areas for assigned programs for approval or life-cycle management of the BMS pipeline. Key responsibility of this role is to lead the Myeloma disease team consisting of a cross functional team of asset and disease scientists with deep disease, drug development and business knowledge for overall translational strategy working closely with discovery and early development teams, late clinical development as well as with a hematology laboratory group.

**Technical Skills**:

- In-depth understanding of Oncology or Hematological cancers, especially Multiple Myeloma,, clinical landscape, evolving therapy, competitive landscape
- Strong understanding of clinical, translational and mechanistic data with therapeutics development
- Strong background in genetics, cancer biology and/or immunology
- Strong background in strategy development preferably in hematology
- Understanding of late-stage drug and translational development process - Proven track record of drug submissions, approvals, regulatory interactions and label negotiations
- Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, disease strategies, mechanism slides, regulatory submissions, strategic communications, literature/market/pt segment analyses - Proven scientific/project leadership expertise (working in teams, managing people/projects)
- Ability to synthesize complex scientific and business problems into strategy and tactics
- Basic understanding of IP, contracting terms and provisions

**Responsibilities**:
In coordination with Head of Strategy and Execution, builds disease area specific long term translational strategy and implementation across portfolio:

- Leads the development of disease, portfolio, or asset specific translational annual goals and objectives for the Heme TMDT (for internal /external, translational collaboration, compound specific plans etc), open research questions, and is accountable for their progress monitoring in association with Heme TMDT asset and disease scientists
- Assists in developing and maintaining group budget and workforce plan
- Represents Translational Medicine (TM) in cross-functional Strategy and Global Project Teams
- Interfaces with commercial including early commercialization group and Medical Affairs to provide scientific support for cross-functional TM goals
- Assists in managing key strategic and/or collaborative projects along with TM scientists
- Supports regulatory submissions, regulatory interactions, writes translational sections for regulatory response and answers to regulatory queries for the TM group
- Communicates regularly and prepares and makes presentations within the department and externally as required
- Participates in translational research with the Heme TMDT Lab
- Oversees genomic analyses from human clinical samples, cell screens (ie, for resistance mechanisms, PD, biomarkers) and clinical trial support (defined clinical experiments from the development teams). This includes development of high dimensional bioinformatics in collaboration with the Informatics and Predictive Sciences group
- Responsible for delivery of Clinical PD or Biomarker assays, translated from discovery (if applicable or approp