Director, Clinical Science

3 weeks ago


Cambridge, United States Foghorn Therapeutics Inc. Full time

Our Culture: Why work with us?

At Foghorn Therapeutics, we believe in "People First, Mission Always."

We put "People First" because we know our people are the key to everything we will accomplish. We value the diversity of background, ideas, perspectives and experiences that our team members bring to Foghorn Therapeutics - demonstrated by our community speaking more than 22 languages and representing over 24 nationalities. We value our teammates as people, not just as employees - validated by our actions that let our people know that we care about them, their families, and their lives.

We say "Mission Always" because we know a relentless commitment to our mission will make a difference in the lives of others. We believe our success will come from evaluating the data to follow the science. We work hard to develop a new class of therapies that could improve the lives of over 2.5 million people with cancer.

Our culture is focused on succeeding through the evaluation of data, not people. And in that, relationships can flourish and develop.

Our Science:

The groundbreaking science behind our therapies continues to yield vital insights into diseases that have confounded physicians and researchers. Our core scientific approach is centered on the chromatin regulatory system, which opens and closes the right sections of DNA at the right time. Breakdowns in the chromatin regulatory system lead to a wide range of diseases, including cancer, impacting millions of people.

Our proprietary Gene Traffic Control platform is a powerful tool for understanding and modulating the chromatin regulatory system. We are pursuing multiple treatments for breakdowns in this system. We are the only company with the ability to study and target the chromatin regulatory system at scale, in context, and in an integrated way.

The Role:

As the Director of Clinical Science at Foghorn, a leader in the development of innovative oncology treatments, you'll guide the advancement of clinical programs that transform the lives of patients. Leading the strategic design, implementation, and analysis of clinical trials, you'll uphold the highest standards of scientific rigor and ethical research. Your insights will drive critical decision-making, ultimately bringing novel and life-changing therapies to those in need.

In This Role, You'll Get To:

* Champion Strategic Clinical Development: Provide expert guidance on Phase I/II/III programs, crafting protocols and clinical development plans that advance scientific objectives and rigorously adhere to regulatory standards.
* Analyze and Interpret Clinical Data: Diligently oversee the collection and analysis of clinical data, using sophisticated tools to ensure data integrity and offer actionable insights that drive program decisions.
* Optimize Trial Processes: Collaborate with data management to streamline clinical databases and data collection, maximizing efficiency and accuracy.
* Uphold Regulatory Compliance: Safeguard trial integrity by meticulously monitoring adherence to all ethical and regulatory guidelines, swiftly addressing potential issues.
* Contribute to Regulatory Submissions: Support the preparation of scientifically sound and compliant documents for regulatory interactions.
* Disseminate Clinical Knowledge: Support the creation of presentations, publications, and conference materials that advance understanding within the field.
* Nurture Cross-Functional Excellence: Build strong partnerships throughout the organization, bridging the gap between clinical science, pharmacology, medicine, and regulatory functions.



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