Research Associate I/ii, Lnp Formulations

4 days ago

Somerville, United States Tessera Therapeutics Full time

**Company Summary**:
Tessera Therapeutics is pioneering Gene Writing— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.

The Research Associate will be responsible for developing LNP formulations and processes to support company's in vitro and in vivo pre-clinical studies. We are searching for a driven, enthusiastic, and self-motivated individual who is comfortable multitasking and working independently on various aspects of the platform. This individual will join a dynamic, rapidly growing, and highly collaborative team.

**Key Responsibilities**:

- Strengthen Tessera's gene editing delivery platforms by formulating and developing novel LNPs
- Routinely formulate nucleic acid payloads to support company's in vitro and pre-clinical studies
- Utilize physicochemical testing methods to screen and characterize novel LNP formulations
- Maintain thorough and detailed electronic lab notebooks (ELNs) and documentation records
- Work both independently and as part of a team to adapt to changing priorities in a fast-paced environment
- Assist in maintaining general laboratory functionality, including lab equipment maintenance and the ordering, and receiving of lab supplies
- Adhere to all laboratory safety requirements and procedures

**Basic Qualifications**:

- BS with up to 4 years of experience, or MS and up to 2 years of experience. Degrees in Chemistry, Chemical Engineering, Biomedical Engineering, Material Science, or closely related field is required.
- Prior experience in LNP delivery or formulations
- Strong communication and collaboration skills
- Highly organized and detail-oriented
- Prior experience with scientific and experimental documentation

**Preferred Qualifications**:

- Proven ability to work with a high level of integrity, accuracy, and attention to detail
- Strong organizational skills that enable a high level of productivity and timely completion of assignments
- Excellent oral and written communication skills for effectively interfacing with all members of the company
- Ability to excel in a dynamic, fast-paced, and highly collaborative environment
- Ability to troubleshoot process equipment and analytical instrumentation
- Deliver effectively on time sensitive assignments, and document/communicate scientific data
- Perform experiments that involve preparation and physiochemical characterization of nanoparticles
- Supply LNP test articles for biological studies
- Possess a strong work ethic and good documentation practices, including electronic laboratory notebook and inventory maintenance
- Perform duties according to applicable safety procedures
- Knowledge of nucleic acid chemistry and biology

**More about Tessera Therapeutics**:
Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits currently include group medical, vision and dental coverage, group life and disability insurance, 401(k) with company contribution, tuition reimbursement, and much more.

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