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Principal Research Scientist I Chemistry
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North Chicago, United States AbbVie Full timeJob DescriptionJob DescriptionCompany DescriptionAbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and...
Associate Scientist, I
3 months ago
**Company Description**
AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott. AbbVie combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader to develop and market advanced therapies that address some of the world's most complex and serious diseases.
**Role Overview**
Within Small Molecule Chemistry and Manufacturing Control (CMC) Development, Analytical Research & Development focuses on utilizing measurement scientists of analytical chemistry to inform the development of new chemical entities and the associated formulations dosed in a preclinical and clinical setting across a wide range of pipeline programs. The group is highly cross-functional and works closely with internal Analytical R&D colleagues as well as colleagues within Discovery, Process Chemistry, Pharmaceutics and Drug Product Development.
**Key Responsibilities**
- Responsible for performing method development and execution of methods (e.g. (U)HPLC with UV/Vis or MS detection, Karl Fischer titration, GC with FID or MS detection, dissolution, physical measurements, etc.) for the characterization and development of small molecule active pharmaceutical ingredients, intermediates, starting materials, pre-clinical formulations, and accelerated stability samples.
- Independent and productive in performing lab work with team lead guidance, including, but not limited to, solution and sample preparations, stability studies, instrument maintenance, and buffer preparations, after appropriate training.
- Troubleshoot basic technical issues with team lead guidance.
- Responsible for efficiently processing and visualizing analytical data and summarizing basic trends within the data.
- Responsible for maintaining and keeping an accurate laboratory notebook with high attention to detail.
- Validate analytical methods and perform testing on clinical supplies, following current Good Manufacturing Practices (cGMPs).
- Member of functional and cross-functional teams driving business initiatives, executing activities with team lead supervision and guidance.
**Qualifications**
- Bachelors degree in Pharmaceutical Chemistry, Analytical Chemistry, or Organic Chemistry
- Self-motivated, hard-working, detail-oriented individual able to work in a fast-paced team environment.
- High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.
- Working knowledge of analytical chemistry concepts with capability and/or willingness to develop and execute analytical methods.
**Preferred**
- Hands-on experience with analytical chemistry techniques including titration, (U)HPLC, and mass spectrometry.
**Key Leadership Competencies**
- Builds strong relationships with peers as well as partners outside of the department to enable a productive cross-functional working environment.
- Able to prioritize assigned tasks and execute multiple activities in a given week.
- Learns fast, applies knowledge and is agile enough to change course quickly where indicated.
**Additional Information**
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is a considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
