Postdoctoral Fellow

1 month ago


Houston, United States Baylor College of Medicine Full time

**Summary**:
Baylor College of Medicine has an opportunity for a Postdoctoral Research Associate position with a focus on identifying immune, inflammatory, metabolic, and epigenetic drivers of post-infectious morbidity and mortality. The study will evaluate 300 pneumonia patient participants to identify which inflammatory, immune, transcriptomic, epigenomic, and metabolic marks are associated with post-pneumonia morbidity and mortality. Single cell technology will be implemented to identify drivers of post-infectious inflammation. Excellent applicants will need a wet lab experience in immunology, flow cytometry, and cellular metabolism, and should have a strong foundation in bioinformatic analysis. (Examples of previous work includes PMID 35169026, 35256539, 32125282).

**Job Duties**:

- Implements measurements of inflammation, host immunity, and cellular metabolism from ex vivo PBMCs and plasma from patients recovering from pneumonia, HIV, or Tuberculosis.
- Implements and analyzes single cell RNA-Sequencing, single cell ATAC-Seq, CITE-Seq, as well as bulk RNA-Seq, Proteomics, Metabolomics, and Lipidomics datasets, generated from pneumonia tuberculosis patient cohorts with rich clinical data.
- Conducts advanced modeling of post tuberculosis lung disease risk using approaches including generalized linear models and deep learning.

**Minimum Qualifications**:

- Ph.D. in Basic Science, Health Science, or a related field.
- No experience required.

**Preferred Qualifications**:

- Ph.D. in Biology, Immunology, Computer Science, or Bioinformatics.
- Excellent written and verbal English skills, strong communication and interpersonal skills, and must be capable of working with large collaborative teams.



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