Senior Scientist, In Silico Discovery
Save this job and keep your search organized
Create a free account to save jobs, create alerts and return to this listing from your dashboard.
By continuing, you agree to our Terms & Privacy Policy.
Senior Scientist in In Silico Discovery within Johnson & Johnson's Therapeutics Discovery, focused on developing and deploying structure-based, physics-driven computational workflows for early drug design.
Responsibilities:
- build and optimize automated protocols for ligand/protein prep, docking, free energy calculations, and co-folding
- enhance workflow automation, expand scope, and integrate new tools
- collaborate with IT and platform teams to align with enterprise standards
- leverage AI to accelerate development
Requirements:
- PhD in computational science or chemistry
- expertise in structure-based drug discovery, programming (preferably Python), and automated workflow development
- familiarity with software engineering best practices
Preferred:
- experience with open-source libraries like RDKit, AI/ML platforms, agentic AI, and advanced methods such as free energy calculations and co-folding
- postdoctoral or industry experience in drug discovery advantageous
High-Value:
- Computational chemistry
- automation in early-stage biologics or small molecules
- emerging technologies
- cross-functional collaboration in global teams
Work setup:
primarily Belgium, with options in California or Pennsylvania; travel up to 10% domestically and internationally.
-
Senior Scientist, Oncology In Vivo Discovery
4 days ago
Spring House, PA, United States Johnson & Johnson Innovative Medicine Full-time $120,000 - $180,000Johnson & Johnson Innovative Medicine seeks a Senior Scientist in Oncology Discovery at Spring House, PA. Lead in vivo and ex vivo programs, coordinate cross‑functional teams, and drive development of cancer therapies from bench to bedside.You will mentor scientists and contribute to publications, with a focus on translational cancer biology, imaging, and
-
Spring House, PA, Montgomery County, PA; Pennsylvania, United States Johnson & Johnson Full-timeSenior Scientist position in oncology discovery at Johnson & Johnson focused on in vivo pharmacology studies for cancer therapeutics. The role involves designing and executing preclinical studies, leading cross-functional teams, and advancing small molecules, biologics, and cell therapies from laboratory to clinical development. Responsibilities
-
Senior Scientist, Oncology In Vivo Discovery
5 days ago
Spring House, PA, United States 6084-Janssen Research & Development, LLC Legal Entity Full-time $150,000 - $190,000Johnson & Johnson is seeking a Senior Scientist in Oncology Discovery at Spring House, PA. You will drive in vivo pharmacology studies across small molecules, biologics, and cell therapies for cancer, coordinating cross-functional teams and ensuring regulatory compliance.You will mentor junior scientists, manage multiple projects, and contribute to ex vivo...
-
Spring House, PA, United States 6084-Janssen Research & Development, LLC Legal Entity Full-time $150,000 - $190,000At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across...
-
Principal Scientist, AI-Native Discovery
3 days ago
Spring House, PA, United States J&J Family of Companies Full-timeAt Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across...
-
AI-Driven Biologics Discovery Scientist
5 days ago
Spring House, PA, United States 6084-Janssen Research & Development, LLC Legal Entity Full-time $117,000 - $201,000Johnson & Johnson Innovative Medicine is recruiting a Principal Scientist, AI-Native Discovery (Large Molecules) to join the In Silico Discovery team. Located in Spring House, PA (preferred) with options in Cambridge, MA or San Diego, CA, travel may be required.You will shape AI-native biologics discovery by integrating advanced AI, predictive modeling, and
-
Spring House, PA, Montgomery County, PA; Pennsylvania, United States Johnson & Johnson Innovative Medicine Full-timeAt Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate...
-
Principal Scientist, AI-Native Discovery
4 days ago
Spring House, PA, Montgomery County, PA; Pennsylvania, United States Johnson & Johnson Full-timePrincipal Scientist role in AI-native biologics discovery within Johnson & Johnson's In Silico Drug Discovery team. The position integrates artificial intelligence, computational design, and predictive modeling into therapeutic discovery programs across three U.S. locations. Responsibilities Connect biologics
-
Principal Scientist, AI-Native Discovery
5 days ago
Spring House, PA, United States 6084-Janssen Research & Development, LLC Legal Entity Full-time $117,000 - $201,000At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the...
-
Director, Autonomous Lab AI
2 days ago
Spring House, PA, United States Johnson & Johnson Co. Full-timeJohnson & Johnson is recruiting for a Director, Physical AI for Autonomous Discovery to join the In Silico Drug Discovery team. The preferred location is Spring House, PA, with travel as needed; Cambridge, MA nearby options may be considered. No remote option.The role leads the Physical AI strategy, combining AI, robotics, and scientific reasoning to enable...