Senior Scientist, Discovery- Oncology In Vivo
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Senior Scientist position in oncology discovery at Johnson & Johnson focused on in vivo pharmacology studies for cancer therapeutics. The role involves designing and executing preclinical studies, leading cross-functional teams, and advancing small molecules, biologics, and cell therapies from laboratory to clinical development.
Responsibilities
- Design, execute, and interpret in vivo pharmacology studies independently for oncology target validation and therapeutic agent characterization
- Develop and optimize in vivo models for efficacy, mechanism of action, PK/PD, and dose-schedule evaluations across diverse cancer types
- Lead preclinical cancer studies while ensuring scientific rigor, regulatory compliance, and quality standards
- Mentor junior scientists and contribute thought leadership across research programs and external partnerships
- Analyze and present data using statistical methods for internal stakeholders and external publications
Requirements
- Bachelor's degree in life sciences with 10+ years pharma/biotech experience, or Master's with 7+ years, or PhD with 1-3 years post-graduate experience
- Demonstrated expertise with oncology xenograft and syngeneic mouse models
- Proficiency in small molecule and/or biologics development
- Strong technical skills in tumor implantation, dosing, measurement, and data analysis
- Experience with flow cytometry, IHC, ELISA, RT-PCR, or similar analytical techniques
- Ability to manage multiple concurrent projects with meticulous attention to detail
- Excellent communication and cross-functional collaboration capabilities
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