Global Commercial Director T2D, CVRM

Join to apply for the Global Commercial Director T2D, CVRM role at AstraZeneca At AstraZeneca we turn ideas into lifechanging medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. Were focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine. Within our BBU CVRM franchise, weve established a new commercial area focused on Weight Management and Type 2 Diabetes (T2D). Our ambition is to deliver a portfolio of simple, scalable, and sustainable solutions that improve health and wellbeing, reduce cardiometabolic risk and protect organs for people living with diabetes, overweight, and/or obesity. To achieve this, were seeking an experienced commercial leader to shape the launch strategy for one of our lead assets in T2D and related cardiometabolic conditions. This is a pivotal prelaunch role that defines how we bring the science to market and prepare the organization for launch success. The role reports to the Global Commercial Head Weight Management. Key Responsibilities Lead development of a global gotomarket (GTM) strategy including market segmentation, positioning, target audiences, and launch sequencing. Translate strategic objectives into an actionable global prelaunch roadmap, defining the value proposition, brand narrative, and engagement approach. Partner with regional and country commercial leaders to ensure global alignment and adaptability to local market realities. Create and socialize a clear brand strategy that balances scientific differentiation with emotional resonance across key stakeholders (HCPs, payers, patients, advocacy). Lead deep analysis of market dynamics, competitive environment, and evolving treatment paradigms to anticipate opportunities and risks. Partner with Insights, Analytics & Forecasting teams to generate actionable market and customer insights that inform TPP design, clinical plans, and launch assumptions. Develop and execute marketshaping initiatives including awareness, diseaseeducation, and earlyaccess strategies to create readiness ahead of launch. Build external validation loops through advisory boards, stakeholder mapping, and cocreation with key opinion leaders and advocacy groups. Partner closely with R&D, Clinical, Regulatory, Medical Affairs, Pricing & Market Access and Global Product Teams to ensure the commercial voice is embedded early in development. Align global functions around clear prelaunch milestones (e.g., TPP validation, pricing strategy, access readiness, global narrative, and launch framework). Define and track KPIs to measure organizational readiness and strategic progress toward launch. Collaborate with regional/country teams to ensure knowledge transfer, toolkit development, and capability building for firstwave markets. Oversee creation of core global brand assets and messaging frameworks to ensure consistency across markets and channels. Manage relationships with creative and strategic agencies, consultants, and other thirdparty partners to develop prelaunch materials and campaigns. Lead development of the brand identity system naming, tone of voice, and creative direction in alignment with AstraZeneca standards and scientific integrity. Serve as a key member of the Global Commercial Leadership Team, ensuring transparency of strategy, timelines, and investment decisions. Present GTM recommendations, forecasts, and business cases to governance boards and senior leadership. Foster strong collaboration across functions and geographies; champion a culture of curiosity, accountability, and evidencebased decision making. Essential Skills / Experience Bachelors degree required; advanced degree (MBA, PhD, or MSc) preferred. 10+ years experience in pharmaceutical commercial strategy or marketing, ideally in prelaunch or early launch settings. Relevant experience in TA: cardiometabolic, obesity, or T2D. Strong track record in developing and executing gotomarket or brand strategies that integrate insight generation, forecasting, and positioning. Proven ability to collaborate across scientific, regulatory, and commercial interfaces to drive alignment. Excellent analytical, strategic, and communication skills; comfortable influencing at senior levels in a matrixed environment. Selfstarter with high energy, intellectual curiosity, and the ability to lead through ambiguity. Desirable Skills Experience in US or other large market. Previous experience in global role. Direct experience in market shaping, disease education, or prelaunch activation. Strong working knowledge of pricing, reimbursement, and access strategy. Familiarity with digital ecosystem development and omnichannel stakeholder engagement. Benefits and Work Culture When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire lifechanging medicines. Inperson working gives us the platform to connect, work at pace, and challenge perceptions. Thats why we work, on average, a minimum of three days per week from the office, but we balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. Earnings & Benefits The annual base pay for this position ranges from $229,303 to $343,955. Hourly and salaried nonexempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, jobrelated knowledge, skills, and experience. In addition, our positions offer a shortterm incentive bonus opportunity; eligibility to participate in our equitybased longterm incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered include a qualified retirement program (401(k) plan); paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an atwill position, and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Application Ready to jump in and be part of something extraordinary? Apply now and take the next step in your career journey with AstraZeneca EEO Statement Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. Date Posted 26-Nov-2025 Closing Date 11-Dec-2025#J-18808-Ljbffr