Senior Medical Director Clinical Development

United States – Upper Providence, PA or Waltham, MA (minimum two days a week on site required) Senior Medical Director, Clinical Development – Rheumatology/Immunology We are seeking an experienced physician to lead clinical and scientific strategies for advanced‑stage assets in immunology and fibrosis. The role will shape treatment for complex diseases by steering the development of new, established, and emerging indications within the immunology and fibrosis portfolio. Key Responsibilities Lead the end‑to‑end clinical development strategy for a drug or program, managing specific plans for products and/or indications. Oversee the Integrated Evidence Plan (IEP) and Clinical Development Plan (CDP), including component trials and the Target Medicine Profile (TMP). Ensure clinical study designs align with the IEP and CDP, integrating scientific rationale, regulatory requirements, product development, and commercial goals. Establish and deliver clinical development timelines, defining key decision points and Go/No‑Go criteria. Collaborate with Commercial, Research, Regulatory, Clinical Operations, Statistics, and other internal teams, serving as the clinical point of contact for senior management. Contribute to strategic and organizational initiatives in Clinical Development, including Business Development and due diligence projects. Build and manage external relationships with scientific experts to align programs with business strategy and patient needs. Assess and mitigate risks, evaluate technical success probabilities, and identify opportunities that deliver significant patient benefits. Support global regulatory submissions and interactions, including briefing documents and responses. Champion innovative methods and processes within clinical development, fostering stakeholder engagement and business solutions. Basic Qualifications Medical degree with board certification in Rheumatology or Allergy/Immunology. Experience in the biopharmaceutical industry with clinical drug development in Rheumatology or Immunology. Proven track record in planning clinical development for a Rheumatology or Immunology asset or indication. Experience with Phase 2 and Phase 3 trial design, initiation, execution, and closure. Experience with global regulatory filings and submissions. Knowledge of immunologic‑mediated diseases, underlying biology, and therapeutic targets. Preferred Qualifications Deep experience in Rheumatology, Autoimmune disorders, or the Neuroinflammation space. Solid understanding of regulator, payer, and prescriber priorities in relevant markets. Collaborative experience working with multiple stakeholders on complex projects. Record of building and maintaining strong internal and external stakeholder relationships. Compensation & Benefits The U.S. annual base salary for this position ranges from $270,600 to $451,000. In addition, the role offers an annual bonus and eligibility to participate in GSK’s share‑based long‑term incentive program. Benefits include health care, retirement, paid holidays, vacation, and paid caregiver, parental, and medical leave. Salary ranges are determined based on location, experience, and market rates. Please visit GSK U.S. Benefits Summary to learn more about our comprehensive benefits program. About GSK GSK is a global biopharma company dedicated to uniting science, technology, and talent to advance disease prevention and treatment. We focus on respiratory, immunology, and inflammation; oncology; HIV; and infectious diseases, impacting the health of 2.5 billion people worldwide. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1‑877‑694‑7547 (U.S. toll free) or +1 801 567 5155 (outside the U.S.). Equal Opportunity Employer GSK is an equal opportunity employer. Qualified applicants will receive equal consideration for employment regardless of race, color, religion, sex, marital status, national origin, disability, or any other protected characteristic. We comply with all applicable laws and regulations and do not discriminate based on any of the above factors. GSK does not accept referrals from employment businesses or agencies unless prior written authorization is obtained. We are not liable for any fees resulting from unauthorized referrals. EEO Statement This position represents a true and well‑defined role with a clearly defined job function, skills, responsibilities, and required experience. A complete job description is required for any job posting, inclusive of qualifications, responsibilities, and required experience. All applicants are invited to apply. #J-18808-Ljbffr