Senior Medical Director, Clinical Development

Site Name: USA - Pennsylvania - Upper Providence, USA - Massachusetts - Waltham Posted Date: Oct 30 2025 Are you driven by the opportunity to lead clinical and scientific strategies for advanced-stage assets in immunology and fibrosis, shaping the future of treatments for complex diseases? If so, the Senior Medical Director, Clinical Development - Rheumatology/Immunology role could be an exciting opportunity to explore. GSK seeks a Senior Medical Director, Clinical Development to provide clinical and scientific leadership for potential new, established, and emerging indications for advanced stage assets in the immunology and fibrosis portfolio. The Senior Medical Director, Clinical Development will work with medicine teams to plan and assure delivery of clinical research and development activities. As well as working with early development teams to plan clinical development programs and establish efficient collaboration enabling seamless transition from early to late phase of development. PLEASE NOTE: This career opportunity requires an on-site office presence (minimum of two days a week) at one of GSK's US (Upper Providence, PA or Waltham, MA) sites. Key Responsibilities: Lead the end-to-end clinical development strategy for a drug or program. Manage specific clinical development plans for product(s) and/or indication(s) in specific therapy/disease areas. Oversee Integrated Evidence Plan (IEP), Clinical Development Plan (CDP) and its component clinical trials; be accountable for clinical aspects of Target Medicine Profile (TMP). Provide strategic leadership, for example in assuring that the clinical study designs are aligned with the IEP and CDP, and consider the scientific rationale, regulatory requirements, product development plan and commercial goals. Establish and deliver clinical development timelines, enabling key decision points and Go/No Go criteria for the CDP. Collaborate with internal teams (Commercial, Research, Regulatory, Clinical Operations, Statistics etc.) and act as the clinical point of contact for senior management. Contribute to the strategic and organizational initiatives in Clinical Development, along with Business Development activities, including due diligence projects. Build and manage external relationships with a range of scientific external experts to align clinical programs with business strategy and patient needs. Assess and mitigate risks, evaluate technical success probabilities, and identify transformational opportunities with significant patient benefits. Contribute to global regulatory submissions and interactions, including briefing documents and responses. Champion implementation of innovative methods and processes within clinical development and gain stakeholder support; encourages others to think differently and produce business solutions. Basic Qualifications: Medical degree and clinical medical specialty board qualification in Rheumatology or Allergy/Immunology. Experience in (bio-)pharmaceutical industry with experience in Rheumatology or Immunology clinical drug development. Experience with planning clinical development for a Rheumatology or Immunology asset and/or indication. Experience in drug development, including Phase 2 and Phase 3 clinical trial design, initiation, execution, and closure. Experience of global regulatory filings/submission. Experience of immunologic-mediated diseases, underlying biology, and potential therapeutic targets. Preferred Qualifications: Deep experience in Rheumatology, Autoimmune, or the Neuroinflammation space. Solid understanding of needs and priorities of regulators, payers, and prescribers in relevant global market(s). Experience collaborating with multiple stakeholders on complex projects. Record of building and maintaining strong relationships with internal and external stakeholders. The US annual base salary for new hires in this position ranges from $270,600 to $451,000. The US salary ranges take into account a number of factors including work location within the US market, the candidate's skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave. If salary ranges are not displayed in the job posting for a specific country, the relevant compensation will be discussed during the recruitment process. Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/ #J-18808-Ljbffr