Sr Bioinformatics Scientist

Sr Bioinformatics Scientist – Tempus AI Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real‑world evidence to deliver real‑time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. We are looking for a highly motivated and capable senior bioinformatics scientist with extensive experience and interest in developing cutting‑edge assays and algorithms in the liquid biopsy space (including molecular residual disease (MRD), therapeutic response monitoring (TRM), therapy selection, complete genomic profiling, and diagnostics). Responsibilities Develop novel assays, algorithms, machine learning and statistical models to detect oncology related biomarkers from cell free next‑generation sequencing (NGS) data Design and conduct analyses applying deep genomic and epigenomic knowledge to derive key insights from large multi‑modal datasets Design and execute experiments to characterize performance and support various regulatory submissions. Produce high quality and detailed documentation for all projects. Communicate results with other scientific teams as well as product and bioinformatics leadership. Lead, mentor and/or train other scientists and engineers Qualifications Must have completed a Ph.D. in Bioinformatics, Computational Biology, Cancer Biology, Genetics, Immunology, Molecular Biology, or Computer Science At least 5-10 years of industry or academic experience Computational skills using Python and/or R Proven scientific reputation as demonstrated by scientific publication and/or contribution to successful product development in industry Expertise in developing NGS pipelines using contemporary tools for processing and analyzing NGS data (including methylation, DNA, RNA) within a high performance computing environment In‑depth knowledge of creating statistical models and developing predictive or prognostic algorithms Demonstrated effective communication and presentation skills Self‑driven and works well in interdisciplinary teams The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position. Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles, Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act. We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. Seniority level Mid‑Senior level Employment type Full‑time Job function Research, Analyst, and Information Technology #J-18808-Ljbffr