Scientist/Sr. Scientist, Mechanistic Pharmacology

2 weeks ago

Boston, United States Superluminal Medicines Inc. Full time

About the roleSuperluminal Medicines is seeking a highly motivated and collaborative Scientist / Sr Scientist with experience in drug discovery and GPCR pharmacology to join their growing Biology team and foster the discovery of new medicines. This is a target- and biology-first drug discovery organization that applies AI/ML methods to common drug development bottlenecks, while integrating biology, chemistry, and computation. This is a unique opportunity to build a fruitful career, apply biology expertise to real-world problems, advance the practice of drug discovery, address unmet healthcare needs, and help patients worldwide.Key responsibilitiesProvide robust biology support for Superluminal Medicines's research programs.Think critically through target biology and formulate experimental plans to guide project trajectory.Strategize and conduct cell biology experiments to support program enablement, drug discovery workflows, and mechanism of action evaluations.Demonstrate initiative and discipline to execute experiments following established procedures and suggest improvements to experimental design.Interpret and effectively communicate results to interdisciplinary teams composed of chemists, computational biologists, and machine learning scientists, in an environment that values scientific integrity and quality.Advance external collaborations and outsourced studies.Prepare technical reports to support regulatory submissions.Ensure compliance with company practices and procedures, including laboratory notebooks, file management, quality and regulatory guidelines, and safety.Qualifications & SkillsPh.D. in Biochemistry, Biology, Pharmacology, or related discipline with 1-5 years of experience supporting drug discovery programs.Experience as biology lead of an agile team that supports fast implementation and rapid decision making, with coordination between internal and external parties.Theoretical understanding of GPCRs, small molecule pharmacology, cellular signaling pathways, and lead discovery and optimization practices.Technical proficiency in cellular assays and ability to provide high-quality in vitro results.Ability to strategize and implement cellular mechanism-of-action investigations to understand molecular pharmacology for key chemical entities.Strong laboratory techniques to support cell culture and cell-based assays.Enthusiasm for mastering complex laboratory instrumentation and related software for compound handling, cell-based assays, and database archiving.Commitment to fostering collaborations across interdisciplinary teams and managing external partners.Equal Opportunity StatementSuperluminal Medicines is an Equal Opportunity Employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race, color, creed, religion, national origin, age, ancestry, nationality, marital or civil union status, sex, gender, gender identity or expression, sexual orientation, disability, veteran or military status. #J-18808-Ljbffr

  • Scientist/Sr. Scientist, Mechanistic Pharmacology

    2 weeks ago

    Boston, United States Superluminal Medicines, Inc. Full time

    Scientist/Sr. Scientist, Mechanistic PharmacologyAbout Superluminal Medicines:Superluminal Medicines is a generative biology and chemistry company revolutionizing the speed and accuracy of how small molecule medicines are created. The Company’s platform aims to create candidate-ready compounds with unprecedented speed using a combination of deep biology,...

  • Senior Scientist

    1 week ago

    Boston, United States Superluminal Medicines, Inc. Full time

    A biotech company in Boston seeks a highly motivated Scientist/Sr. Scientist in Mechanistic Pharmacology to join their Biology team. The role involves supporting drug discovery projects, conducting cell biology experiments, and collaborating with interdisciplinary teams. Candidates with a Ph.D. in relevant fields and 1-5 years of experience in drug discovery...

  • Scientist II or Senior Scientist, Pharmacology

    2 weeks ago

    Boston, United States Kymera Therapeutics Full time

    Scientist II or Senior Scientist, Pharmacology Kymera Therapeutics invites applications for the Scientist II or Senior Scientist, Pharmacology position. The role focuses on pipeline projects and target validation in inflammation and related therapeutic areas. Who we are Kymera is a clinical-stage biotechnology company pioneering targeted protein degradation...

  • Scientist, Cell Pharmacology

    2 weeks ago

    Boston, United States Merck Full time

    Job DescriptionJob DescriptionOur Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to...

  • Pharmacology Scientist

    2 weeks ago

    Boston, United States Kymera Therapeutics Full time

    A leading biotechnology company in Boston is seeking a Scientist II or Senior Scientist in Pharmacology to drive innovative drug discovery processes, focusing on assay design and target validation in inflammation. Candidates with a PhD and relevant industry experience are encouraged to apply, with a competitive compensation package available including salary...

  • Senior Scientist, Neuropharmacology

    4 days ago

    Boston, Massachusetts, United States Axonis Therapeutics Full time $120,000 - $180,000 per year

    About Axonis Therapeutics:Axonis Therapeutics is a Boston-based, neuro-focused biotechnology company developing first- and best-in-class medicines targeting KCC2, the critical mediator of inhibition within the brain, by translating breakthrough discoveries spun out from Boston Children's Hospital, Harvard and Laval University. With its proprietary KCC2...

  • Translational Cell Pharmacology Scientist

    2 weeks ago

    Boston, United States MSD Full time

    A biopharmaceutical company in Boston is seeking a motivated Scientist to develop novel pharmacology assays for autoimmune and cancer projects. The ideal candidate will have a strong background in immunology and oncology assays, with responsibilities including assay development and collaboration within global teams. Excellent communication skills and a...

  • Modeling & Simulations Senior Scientist

    2 weeks ago

    Boston, United States Vertex Full time

    Job DescriptionGeneral Summary:The Modeling & Simulations Senior Scientist at Vertex will lead Modeling & Simulation analyses from planning through reporting and align these analyses with the strategy determined by the modeling program lead. Types of analyses can include modeling and simulation to support evaluation of study design, dose selection,...

  • Scientist, Cell Pharmacology

    1 week ago

    Boston, United States Merck Full time

    Job Description The Cell Pharmacology group in the Department of Quantitative Biosciences is seeking a highly motivated scientist with a background in immunology and oncology assays to join our company's research laboratories in Boston. The primary responsibilities will be to develop and characterize novel in vitro and ex vivo translational pharmacology...

  • Scientist, Cell Pharmacology

    3 weeks ago

    Boston, United States MSD Malaysia Full time

    **Job Description**The Cell Pharmacology group in Department of Quantitative Biosciences is seeking a highly motivated Scientist with a background in immunology and oncology assays to join our Company's Research Laboratories in Boston. The primary responsibilities of the successful candidate will be to develop and characterize novel in vitro and ex vivo...