Senior Director, R&D Data Science

Company: Johnson & Johnson Location: Cambridge, MA (preferred) – Spring House, PA; Titusville, NJ; San Diego, CA Employment Type: Full TimeDate Posted: 10/15/2025 Senior Director, R&D Data Science & Digital Health – Ophthalmology Job Function: Data Analytics & Computational SciencesJob Sub Function: Data Science Portfolio ManagementJob Category: People Leader Job Description Lead the data science and digital health strategy for ophthalmology, driving innovation through multiomics, digital health technologies, artificial intelligence, and real‑world evidence. Partner with cross‑functional teams to accelerate drug discovery, development, and patient impact. Role Summary Develop and execute a comprehensive strategy that integrates computational biology, AI/ML, digital health, and clinical/RWE insights. Deliver novel endpoints, patient stratification, and translational discoveries that shape the future of ophthalmic therapeutics. Key Responsibilities Define and execute the data science and digital health strategy for ophthalmology, integrating computational biology, AI/ML, digital health, and clinical/RWE insights. Drive the application of multiomics (genomics, proteomics, transcriptomics, metabolomics, etc.) and integrative analytics to uncover disease mechanisms, biomarkers, and novel targets. Lead the development, validation, and regulatory engagement of digital tools and novel endpoints to enhance clinical trial design, patient monitoring, and care pathways. Champion the use of machine learning, deep learning, generative and agentic AI to accelerate patient stratification, disease modeling, and translational discovery. Partner with clinical development and medical affairs to integrate RWE into evidence generation, supporting trial optimization, regulatory submissions, and real‑world impact assessment. Build strong cross‑functional and external collaborations with academic groups, technology providers, regulators, and consortia. Recruit, develop, and inspire a diverse team of digital health scientists, RWE experts, and computational scientists. Qualifications Advanced degree (PhD, MD, or equivalent) in neuroscience/quantitative sciences such as biomedical engineering, data science, biostatistics, or computational biology. 10+ years of relevant industry or academic experience with proven leadership in data‑driven drug discovery and development. 7+ years of experience as a people manager. Experience in clinical development within ophthalmology preferred. Excellent communication skills, translating complex data insights into clear strategies for senior stakeholders. Technical expertise in at least two of the following: multiomics integration and advanced statistical/causal inference methods; digital health technologies (wearables, sensors, mobile platforms); large‑scale clinical datasets, EHR, and real‑world data with advanced modeling and patient stratification. Track record of scientific contributions (presentations and publications) in this field. Familiarity with data standards, privacy regulations, and regulatory qualification pathways. Knowledge of data infrastructures, data analysis pipeline development, and state‑of‑the‑art AI methodologies (a plus). Competence with programming and analytics environments (e.g., Python, R) and ability to guide technical teams at a strategic level. Demonstrated success in leading cross‑disciplinary teams at the interface of data science, biology, and clinical development. Additional Information Hybrid schedule: 3 days on‑site, 2 days remote (no fully remote option). Approximately 25% domestic and international travel. Compensation: Base pay range $193,000–$333,500 per annum. Eligible for annual performance bonus. Benefits include medical, dental, vision, life insurance, short‑ and long‑term disability, and a 401(k) plan. Time Off: Up to 120 hours of vacation, 40 hours of sick time, and up to 13 holiday days per calendar year. EEO Statement Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status, or any other characteristic protected by law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act. If you require accommodations due to a disability, please contact us at https://www.jnj.com/contact-us/careers. #J-18808-Ljbffr