Postdoctoral Fellow

2 weeks ago

seattle, United States HDT Bio Full time

HDT Bio is seeking a highly motivated and talented postdoctoral researcher who has recently completed a Ph.D. The selected candidate will work under the supervision of Dr. Taishi Kimura on a newly awarded NIH/NIAID R01 grant. This project, building on our recently published work (Kimura et al., 2023 Mol Ther., PMID: 37403357; Warner et al., 2024 Sci Transl Med., PMID: 39110777), focuses on the mechanisms by which innate immune signals positively and negatively modulate adaptive immune responses in the muscle local microenvironment where HDT’s vaccines are commonly administered. The research aims to advance the basic understanding of the muscle tissue’s role in the induction of adaptive immunity and to further develop HDT's self-amplifying replicon RNA vaccine technology.


Candidates with prior experience in flow cytometry, mouse handling, T-cell response analysis, and virus infection models will be given top priority. The successful candidate is expected to publish their findings in high-impact journals and is encouraged to apply for fellowship programs. The position is offered on a renewable annual contract, contingent upon satisfactory performance and continued funding.


Applicants should submit a cover letter to Barbara.purmort@hdt.bio in addition to their LinkedIn application, detailing their research experience and explaining how this experience meets the qualifications.


Principal Responsibilities:

Conduct research using mouse models, including handling, breeding, dosing, conducting infection studies.

Operate and maintain flow cytometry equipment and analyze related data.

Design and execute experiments, analyze data, and interpret findings.

Perform and manage experiments involving ABSL2/ABSL2+ virus infection models, ensuring compliance with safety protocols.

Collaborate with multidisciplinary teams, including immunologists, virologists, molecular biologists, and formulation scientists.

Present research findings in team meetings and at national/international conferences.

Prepare manuscripts for peer-reviewed journals.


Qualifications:

Ph.D. in Immunology, Molecular Biology, Microbiology, or a related field.

Strong background in vaccine research and/or immunology.

Experience in cell culture, flow cytometry, virus infection models, and mouse models.

Experience with ABSL2/ABSL2+ infection models is highly preferred but not required.

Excellent communication skills and the ability to work both independently and as part of a collaborative team.

Strong track record of scientific productivity (e.g., publications).


Education/Experience:

Ph.D.


This summary describes a portion of the essential functions/responsibilities of this position. It is not an exhaustive list of all job duties. Management reserves the right to modify the duties of this position as necessary.


HDT Bio is a vaccine and immunotherapy Biotechnology company with next-generation approaches designed to enable the body’s immune system to prevent and cure disease. We have engineered our technologies to Access, Activate, and Amplify the immune system’s natural ability to create antibodies and T-cells that fight cancer and infectious diseases such as SARS-CoV-2. We are developing multiple product candidates from our proprietary discovery platforms, including LION™, which has the potential to provide health benefits to a broad patient population.


HDT Bio offers a comprehensive compensation plan which includes health insurance for employees and dependents (inclusive of multiple plants to choose from, including a $0 premium plan with HSA and company contribution), generous PTO (11 observed holidays and week-long year-end closure), stock options with Carta Tax Advisory for equity and tax support, flexible spending accounts (FSAs), commuting benefits (ORCA or paid parking), and retirement benefits with company match.


HDT Bio Corp. is an equal opportunity employer committed to a diverse and inclusive workforce. This environment is encouraged by HDT's culture, which supports women in science through our Women+ group, creates inclusive events to highlight the diverse cultures represented by our staff, and with the adoption of an open office environment for all. Qualified applicants of any race, color, religion, sex, sexual orientation, gender identity, age, national origin, veteran, or disability status are encouraged to apply. Applicants will be considered for employment without regard to these or any other actual or perceived statuses.

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