Senior Director, Peptide Therapeutics

2 weeks ago

South San Francisco, United States Genentech Full time

The Position

Senior Director, Peptide Therapeutics

Who We Are

The Department of Peptide Therapeutics oversees two technology platforms, disulfide-constrained peptides (DCPs) and macrocyclic peptides (MCPs), which are key drug-discovery modalities for gRED's research pipeline. These two modalities complement our existing drug discovery armamentarium and provide unique capabilities to drug targets that are challenging with our traditional small molecule or antibody approaches. Achieving the Department's Mission is critical for Genentech's drug discovery capabilities as these novel approaches complement our existing biotherapeutics and small-molecule drug discovery platforms, and provide us with a significant competitive advantage. The candidate will report to the Vice President of Early Discovery Biochemistry, and will serve as a member of the Joint Research Committees on external collaborations focused on novel peptide therapeutic modalities.

Who You Are

* You will Create and oversee long-term strategy for technology investments to develop new peptide-based therapeutic and diagnostic modalities essential for next-generation near- and long-term drug discovery platforms.


* Collaborates with Pharma Partnering to create strategic vision and identify external partnerships in the areas of peptide therapeutic discovery and technology, and intracellular delivery technology.


* Leads gRED internal peptide therapeutics modality strategy.


* Partners with gRED Computational Sciences to address gRED peptide therapeutics informatics needs.


* You will provide guidance to VP-Early Discovery Biochemistry on next-generation peptide therapeutics discovery modalities.


* Represents department at Research Review Committee, Research Leadership Team and Research Portfolio Review.



Managerial Responsibilities

* Leads Department of Peptide therapeutics with a team of ~ 25 internal FTEs and ~25 globally distributed contingent staff, to deliver new peptide therapeutics for targeting challenging-to-drug proteins.


* Accountable for critical matrix-leadership of project teams or broader organization.


* Oversees internal and external budget.


* Represents gRED on Joint Research Committees on external collaborations focused on novel peptide therapeutic modalities.


* Lead contact for Pharma Partnering to identify and oversee strategic external partnerships in the areas of peptide therapeutic discovery and technology, and intracellular deliver technology.


* Facilitate partnerships across gRED and pRED to maximize the therapeutic potential of peptide therapeutic modalities in order to "drug the undruggable".



Qualifications:

* Internationally renowned leader in peptide drug discovery technologies as supported by a consistent and strong record of peer-reviewed publications.


* MD, PhD, DVM or equivalent in Chemistry, Biochemistry or related field.


* 10+ years of experience in drug discovery and development, with minimum 3 years experience in a Director role.


* Ability to define long-term strategies for discovery and optimization of peptides in order to 'drug' increasingly more challenging therapeutic targets.


* Strong collaboration skills and experience at successfully influencing stakeholders.


* Excellent communication skills and experience with change management.


* Experience managing/mentoring personnel as demonstrated by successful career advancement of employees.


* External recognition as leader in peptide therapeutic discovery as evidenced by external speaking invitations at conferences/institutions.



Relocation benefits are available for this job posting

The expected salary range for this position based on the primary location of California is $207,600 and $385,500 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

  • Scientific Sr. Director – Peptide Discovery Team

    3 weeks ago

    San Diego, United States Lilly Full time

    We’re looking for people who are determined to make life better for people around the world. This is a technical leadership position (Scientific Sr. Director – Group Leader) in the Peptide Discovery Team within Biotechnology Discovery Research in San Diego. The individual will lead a team of scientists that utilize multiple peptide discovery platforms...

  • Scientific Sr. Director

    2 weeks ago

    San Diego, United States Eli Lilly Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Scientist, Peptide Chem

    15 hours ago

    San Diego, United States Neurocrine Bioscience Full time

    Who We Are: At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options. What We Do: Neurocrine Biosciences...

  • Scientific Sr. Director

    2 weeks ago

    San Diego, United States Eli Lilly Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Scientific Sr. Director – Peptide Discovery Team

    1 month ago

    San Diego, United States Eli Lilly and Company Full time

    At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities...

  • Senior Director, Clinical Pharmacology

    2 weeks ago

    South San Francisco, United States Maze Therapeutics Full time

    The Position: At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Director, Clinical Pharmacology to join our Clinical Science team and take a central role in pioneering the future of...

  • Senior Director, Clinical Pharmacology

    3 weeks ago

    South San Francisco, United States Maze Therapeutics Full time

    The Position: At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Director, Clinical Pharmacology to join our Clinical Science team and take a central role in pioneering the future of...

  • Senior Director, Clinical Pharmacology

    2 days ago

    South San Francisco, United States Maze Therapeutics Full time

    The Position: At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Director, Clinical Pharmacology to join our Clinical Science team and take a central role in pioneering the future of...

  • Senior Director, Clinical Pharmacology

    2 weeks ago

    South San Francisco, United States Maze Therapeutics Full time

    The Position:At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Director, Clinical Pharmacology to join our Clinical Science team and take a central role in pioneering the future of...

  • Senior Director, Clinical Pharmacology

    1 week ago

    South San Francisco, United States Maze Therapeutics Full time

    Job DescriptionJob DescriptionThe Position:At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Director, Clinical Pharmacology to join our Clinical Science team and take a central role...

  • Senior Director, Clinical Pharmacology

    2 days ago

    South San Francisco, California, United States Maze Therapeutics Full time

    The Position:At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Director, Clinical Pharmacology to join our Clinical Science team and take a central role in pioneering the future of...

  • Senior Director, Clinical Pharmacology

    3 weeks ago

    South San Francisco, California, United States Maze Therapeutics Full time

    The Position:At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Director, Clinical Pharmacology to join our Clinical Science team and take a central role in pioneering the future of...

  • Senior Director, Clinical Pharmacology

    2 days ago

    South San Francisco, United States Maze Therapeutics Full time

    The Position: At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for a Senior Director, Clinical Pharmacology to join our Clinical Science team and take a central role in pioneering the future of...

  • Principal Scientist, Peptide Bio-organic Chemistry

    2 weeks ago

    San Diego, United States Clinical Dynamix, Inc. Full time

    Principal Scientist, Peptide / Bio-organic ChemistryThis BioPharma is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric...

  • Scientist, Mass Spectrometry

    1 month ago

    South San Francisco, United States Parvus Therapeutics Full time

    Job DescriptionJob DescriptionParvus Therapeutics Inc. Parvus Therapeutics Inc. is a privately held biopharmaceutical company developing Navacims™, a platform technology based on foundational research published in 2016 (Nature 530:434), to treat autoimmune diseases. Parvus’ mission is to shift the treatment paradigm toward Navacim™-directed immune...

  • Senior Buyer

    3 weeks ago

    South San Francisco, United States CytomX Therapeutics Full time

    **Description** **About CytomX Therapeutics:** CytomX Therapeutics, Inc. is committed to changing the treatment of cancer with our novel Probody therapeutic platform. Our commitment to transforming lives with safer, more effective therapies is driven by our curiosity and passion for innovation and our belief that by acting with integrity in an honest,...

  • Associate Director, Clinical Science

    2 weeks ago

    South San Francisco, United States Maze Therapeutics Full time

    The Position: At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for an Associate Director, Clinical Science to join our Clinical Science team and take a central role in pioneering the future of...

  • Senior Director, CMC Regulatory Affairs

    3 weeks ago

    South San Francisco, United States Allogene Therapeutics Full time

    Job Description About Allogene: Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T™) products for cancer and autoimmune disease. Led by a management team with significant experience in cell therapy, Allogene is...

  • Associate Director, Clinical Science

    3 weeks ago

    South San Francisco, United States Maze Therapeutics Full time

    The Position: At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for an Associate Director, Clinical Science to join our Clinical Science team and take a central role in pioneering the future of...

  • Associate Director, Clinical Science

    2 weeks ago

    South San Francisco, United States Maze Therapeutics Full time

    The Position:At Maze Therapeutics, we are assembling a team of passionate, creative, and dedicated professionals to join us on our mission to turn groundbreaking genetic discoveries into life-saving medicines. We're looking for an Associate Director, Clinical Science to join our Clinical Science team and take a central role in pioneering the future of...