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Scientist - Therapeutic Discovery

2 months ago

thousand oaks, United States Randstad Life Sciences US Full time

Immediate opportunity for a Scientist to support a drug discovery project with a leading biotechnnology company located in Thousand Oaks, CA. You will be a part of the Therapeutic Discovery organization joining the Lead Discovery and Characterization Department in support of Company’s small molecule drug discovery pipeline.


Schedule/Shift: 1st shift, Mon.-Fri

Position Type: 3 mos. contract (through Dec. 2024); potential for extension


Essential Duties and Responsibilities:

  • Optimize and perform routine cell-based assays to support lead identification and mechanism-of-action studies in the development of new therapeutic agents
  • Semi-independently plan and implement experiments, adapt readily to changing project needs and develop sophisticated problem-identification and problem resolution skills
  • Maintain proficiency with the latest scientific literature and rationale surrounding drug targets and be an active contributor to the interpretation of results in group discussions
  • Show excellent collaboration and communication skills as this role requires an ability to work closely with other scientists in the group and across Company
  • Adherence to good laboratory conduct, documentation practices, and safety guidelines


Qualifications:

  • Ph.D. degree training in Cell and/or Molecular Biology or closely related field Or Master's degree (MS) and 2+ years relevant experience.
  • Experience working as part of a multi-disciplinary team in a biopharmaceutical setting and desire to work in cross-functional environments
  • Track record of developing, implementing, and performing cell-based screening assays in microtiter plates to support early drug discovery research
  • Mammalian cell culture
  • Experience and understanding in methods for the analysis of cells (i.e. live-cell imaging, flow cytometry), proteins (HTRF, MSD, ELISA, western blot), and RNA (RT-qPCR, NGS)
  • Subject-matter expertise in induced-proximity therapeutics, targeted protein degradation, or the ubiquitin-proteasome system
  • Excellent time management skills and ability to establish priorities and meet timelines
  • Familiarity with software and statistical platforms for data analysis (GraphPad Prism, R)