EPM Scientific | Director Clinical Pharmacology | san francisco, ca
1 week ago
A leading biotechnology firm focuses on developing innovative cancer therapies that target specific molecular pathways to improve patient outcomes. Their approach combines cutting-edge research with a deep understanding of cancer biology, advancing treatments that address significant unmet medical needs. With a diverse pipeline of both small molecules and biologics, the company strives to bring forward therapies that can make a meaningful impact on patients’ lives. Through collaboration and scientific excellence, they are at the forefront of transforming cancer care with novel, precision-based treatments.
Key Responsibilities
- Develop and execute clinical pharmacology and pharmacometrics strategies to advance Exelixis programs through all stages, from research to post-marketing.
- Serve as the clinical pharmacology lead on project teams, offering expertise in pharmacokinetics (PK)/pharmacodynamics (PD), biopharmaceutics, drug-drug interactions, and quantitative pharmacology.
- Guide the progression of small molecules and biologics through key development milestones, including IND/CTA submissions, EOP2 meetings, and marketing applications.
- Lead or oversee PK/PD and exposure-response analyses using advanced modeling and simulation techniques to support human PK predictions, dose selection and optimization, trial designs, risk/benefit assessments, Go/No-Go decisions, regulatory submissions, and publications.
- Collaborate with cross-functional teams, including Clinical Development, Biostatistics, Discovery, Translational Medicine, CMC, Toxicology, DMPK, Clinical Operations, and Regulatory Affairs, to meet project and corporate objectives.
- Drive the visibility of Exelixis’ scientific expertise through publications and external collaborations.
- Work with both internal and external scientific experts to evaluate and implement new methodologies, maintaining cutting-edge techniques, models, and capabilities.
- Ensure adherence to SHE policies, GxP compliance, and regulatory standards throughout the clinical pharmacology programs.
Experience
- Minimum of 8 years of experience in clinical pharmacology and pharmacometrics.
- Experience in the development of small molecules, large molecules, and new modalities.
- Experience with the submission of INDs, NDAs, BLAs, and global marketing applications.
- Oncology therapeutic area experience is preferred.
- Contributions to translational science and precision medicine objectives
-
san francisco, United States EPM Scientific Full timeA leading biotechnology firm focuses on developing innovative cancer therapies that target specific molecular pathways to improve patient outcomes. Their approach combines cutting-edge research with a deep understanding of cancer biology, advancing treatments that address significant unmet medical needs. With a diverse pipeline of both small molecules and...
-
san francisco, United States EPM Scientific Full timePosition Overview:The role is responsible for leading and managing the design and execution of comprehensive Clinical Pharmacology strategies to meet both commercial and regulatory objectives across multiple functions. This individual will drive the development of pharmacokinetics (PK) and pharmacodynamics (PD) studies, generate new study proposals, and lead...
-
san francisco, United States EPM Scientific Full timePosition Overview:The role is responsible for leading and managing the design and execution of comprehensive Clinical Pharmacology strategies to meet both commercial and regulatory objectives across multiple functions. This individual will drive the development of pharmacokinetics (PK) and pharmacodynamics (PD) studies, generate new study proposals, and lead...
-
san francisco, United States EPM Scientific Full timeThe company is dedicated to discovering and developing groundbreaking therapies to revolutionize cancer treatment. Our team, consisting of experienced leadership and a renowned scientific founder, focuses on translating innovative research into new therapeutic solutions. With a strong history in drug discovery and development, we have been instrumental in...
-
san francisco, United States EPM Scientific Full timeThe company is dedicated to discovering and developing groundbreaking therapies to revolutionize cancer treatment. Our team, consisting of experienced leadership and a renowned scientific founder, focuses on translating innovative research into new therapeutic solutions. With a strong history in drug discovery and development, we have been instrumental in...
-
Director Clinical Pharmacology
1 week ago
San Francisco, United States EPM Scientific Full timeA leading biotechnology firm focuses on developing innovative cancer therapies that target specific molecular pathways to improve patient outcomes. Their approach combines cutting-edge research with a deep understanding of cancer biology, advancing treatments that address significant unmet medical needs. With a diverse pipeline of both small molecules and...
-
Associate Director Clinical Pharmacology
1 week ago
South San Francisco, United States EPM Scientific Full timePosition Overview:The role is responsible for leading and managing the design and execution of comprehensive Clinical Pharmacology strategies to meet both commercial and regulatory objectives across multiple functions. This individual will drive the development of pharmacokinetics (PK) and pharmacodynamics (PD) studies, generate new study proposals, and lead...
-
Senior Director, In Vivo Pharmacology
1 month ago
san francisco, United States HireMinds Full timeSenior Director, In Vivo PharmacologySouth San Francisco, CAOur client is an innovative biotech startup focused on developing a groundbreaking gene therapy platform that uses a unique non-viral approach. The Senior Director, In Vivo Pharmacology, will be a pivotal member of the research team, responsible for designing, implementing, and overseeing in vivo...
-
Senior Director, In Vivo Pharmacology
4 weeks ago
san francisco, United States HireMinds Full timeSenior Director, In Vivo PharmacologySouth San Francisco, CAOur client is an innovative biotech startup focused on developing a groundbreaking gene therapy platform that uses a unique non-viral approach. The Senior Director, In Vivo Pharmacology, will be a pivotal member of the research team, responsible for designing, implementing, and overseeing in vivo...
-
san francisco, United States AL Solutions Full timeJob Title: Medical Director Location: South San Francisco, CA (Hybrid)Overview:Join a Immuno-oncology focused biotech dedicated to developing innovative cancer therapies. As a Medical Director, you’ll lead clinical development programs, provide medical oversight for trials, and collaborate with cross-functional teams to advance our pipeline.Key...
-
Senior Director, In Vivo Pharmacology
2 months ago
South San Francisco, United States HireMinds Full timeSenior Director, In Vivo PharmacologySouth San Francisco, CAOur client is an innovative biotech startup focused on developing a groundbreaking gene therapy platform that uses a unique non-viral approach. The Senior Director, In Vivo Pharmacology, will be a pivotal member of the research team, responsible for designing, implementing, and overseeing in vivo...
-
san francisco, United States Meet Full timeContract Biomarker Operations ManagerWe are seeking a Contract Biomarker Operations Manager to execute and oversee clinical biomarker, genetic, and pharmacodynamic (PD) assessments for early Phase and clinical Pharmacology studies. The ideal candidate will have experience bridging science and clinical operations, managing cross-functional teams, and driving...
-
Medical Director
4 weeks ago
San Francisco, United States GO Staffing Full timeFQHC Network in San Francisco is seeking an NP or PA to be the Medical Director for 2 clinics in San Francisco. Responsibilities include developing and overseeing budgets, patient care, and policy in conjunction with Executive leadership. Please refer to job ID Competitive base salary Full comprehensive benefits package. NHCS/HRSA loan repayment...
-
san francisco, United States AL Solutions Full timeJob Title: Senior Medical DirectorLocation: Hybrid - South San Francisco, CACompany: Exclusive Oncology Biotech PartnerAbout the Role: Aramis Frost is seeking a highly experienced and motivated Senior Medical Director to join his exclusive Oncology Biotech partner. This role is pivotal in driving the clinical development and medical strategy for their...
-
san francisco, United States AL Solutions Full timeJob Title: Senior Medical DirectorLocation: Hybrid - South San Francisco, CACompany: Exclusive Oncology Biotech PartnerAbout the Role: Aramis Frost is seeking a highly experienced and motivated Senior Medical Director to join his exclusive Oncology Biotech partner. This role is pivotal in driving the clinical development and medical strategy for their...
-
san antonio, United States EPM Scientific Full timeGeneral Summary:The company is seeking a Scientist II, Immunology to oversee all scientific activities, including applied research, new product/service development, clinical trials, data analysis, and scientific publication. The candidate will ensure top-notch customer service, addressing feedback to resolve issues and enhance satisfaction.Major Duties and...
-
Director of Clinical Pharmacology
2 weeks ago
san diego, United States Redeployment Full timeDIRECTOR – CLINICAL PHARMACOLOGY JOB TITLE: Director, Clinical Pharmacology LOCATION: San Diego, CA; On-Site; Full Time Redeployment was created to match great people with great Life Science companies! We are seeking an accomplished Director of Clinical Pharmacology to lead clinical pharmacology strategies for a portfolio of small molecule assets. This...
-
Director of Clinical Pharmacology
2 weeks ago
San Diego, United States Redeployment Full timeDIRECTOR – CLINICAL PHARMACOLOGY JOB TITLE: Director, Clinical Pharmacology LOCATION: San Diego, CA; On-Site; Full Time Redeployment was created to match great people with great Life Science companies! We are seeking an accomplished Director of Clinical Pharmacology to lead clinical pharmacology strategies for a portfolio of small molecule assets. This...
-
san francisco, United States Bank of San Francisco Full timeAre you looking to support a fast-growing, fast-paced, client-oriented boutique bank with opportunity to learn and grow? Bank of San Francisco is seeking a temporary Sr. Commercial Loan Servicing Specialist for 3+ months to take ownership of implementing complex transactions onto the servicing platform. The ideal candidate must be able to analyze complex...
-
Associate Director, Quantitative Analytics
4 weeks ago
San Francisco, United States EPM Scientific Full timeAssociate Director, Advanced Analytics San Francisco, CA (On-site) A reputable, mid-size Oncology-focused pharmaceutical company is seeking someone to drive critical analyses leveraging secondary data across product launch performance, digital effectiveness, resource allocation, omnichannel reporting and analytics in their Commercial organization. This will...
