Facilities Engineer

1 month ago

Waltham, United States TScan Therapeutics Full time
Job DescriptionJob Description

Position Summary:

TScan Therapeutics is a clinical stage cell therapy company seeking to revolutionize life-changing therapeutics for patients by identifying novel T cells and epitopes. We are looking for an experienced engineer to join our team as Facilities Engineer, supporting our scientists and operations teams. The ideal candidate should have relevant experience in a biotech facility and basic biotech instrumentation as well as general facilities functions, and enjoy fast-paced, collaborative and vibrant startup culture. A team player with a sense of urgency will thrive in this role.

Responsibilities:

  • This role is key in supporting the startup, certification and ongoing production and maintenance of TSCAN’s clinical GMP manufacturing facility and the operation of the R&D facility.
  • Works cross functionally with various vendors to develop and execute commission and validation packages (i.e. protocols, final reports, creation of SOPs) related to the facility systems (facilities/HVAC/utilities systems).
  • Leads the installation of equipment for the manufacturing and quality control areas.
  • Develops, maintains and executes equipment preventive maintenance(PM) and calibration programs.
  • Works closely with vendors and internal teams for preparation and execution of calibrations and PM’s.
  • Investigates, troubleshoots, and resolves problems which occur during routine operations tied to the facility.
  • Assist with IOQ of GMP equipment.
  • Respond to BMS/EMS alarms.
  • Work with scientists to move/relocate lab equipment.
  • Maintain and manage all facility support infrastructure and vendors (electrician, HVAC, pH system, vacuum system, generator, CO2, Compressed Air, etc.).
  • Team member for facility construction projects.
  • Collaborate with the finance team on annual budget projects for the facility.
  • Partner with our EH&S consultants to maintain a safe working environment.
  • Other duties as they are defined.

Requirements:

  • B.S. in Mechanical or Chemical or biotech Engineering
  • 3-8 years experience with process and/or plant utility systems, preferably in a regulated environment
  • Effective verbal and written communication skills
  • Excellent interpersonal and teamwork skills required to work effectively and efficiently in a team-based environment
  • Adherence to domestic and international GMP regulations
  • Ability to multi-task in a dynamic environment with changing priorities
  • Proficiency with Microsoft products; ability to learn additional software applications

About TScan:

TScan Therapeutics was founded in 2018 by a small group of scientists led by Dr. Stephen Elledge (Harvard Medical School/HHMI). TScan is discovering and developing novel TCR-engineered T cell therapies for the treatment of cancer. TScan’s discovery platform is centered around a breakthrough technology that enables the rapid, comprehensive, and genome-wide identification of the peptide antigen targets of T cell receptors. This technology greatly enhances our ability to understand the specific antigens that drive important disease processes, including tumor cell recognition by the immune system, self-reactivity in autoimmune disorders, and acquired immunity in infectious disease. TScan is using the platform in oncology to discover new TCR/target pairs and to rapidly move novel TCRs into clinical development.

Do YOU have the anatomy of a TScanner?

Our talented, compassionate and intelligent team is what makes TScan a great place to work. Our brand new offices with approximately 140,000 square feet of premium lab and office space is an environment that supports innovation, camaraderie and professionalism. We are driven, passionate, fun, flexible and team oriented. Sound like you? Apply today.

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