Associate Scientist II or Scientist I, In Vivo Antibody Discovery
1 week ago
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube and LinkedIn.
Job DescriptionThe Biotherapeutics and Genetics Medicine department within Discovery Research is seeking a highly motivated research scientist to join the in vivo antibody discovery team at AbbVie Bioresearch Center (ABC). The ABC site, based in Worcester, MA, offers the unique setting where Biologics drug discovery, development and manufacturing coexist in one location. Our team interacts with multidisciplinary groups across AbbVie focused on developing therapies for Immunology, Neurology and Oncology diseases. We utilize innovative immunization approaches, advanced multiplex screening assays and best-in-class automation platforms to enable successful antibody discovery against complex targets.
As an integral part of the group, the ideal candidate will:
- Exercise proficiencies in mammalian tissue culture, molecular techniques, and binding assays such as ELISA, flow cytometry, PCR and molecular cloning
- Execute all phases of in vivo antibody discovery campaigns using hybridoma generation, single B cell discovery isolation including screening, cell culture, antibody characterization and next-generation sequencing.
- Analyze and document results, placing data in proper scientific context through review of relevant literature and report findings at team meetings
- Demonstrate scientific excellence through dedication to multiple projects in a fast-paced multi-disciplinary environment
- Exhibit a can-do attitude with excellent interpersonal and communication skills to multiple teams across different functional areas
Qualifications:
- BS or MS in Biology or other related field with 3-5+ years (BS), or 0-2+ years (MS) of industry or academic experience
- Knowledge of molecular biology and/or immunology concepts
- Experience with aseptic mammalian cell culture technique
- Experience in immunoassays using techniques like flow cytometry, ELISA, homogeneous assays and microscopy
- Understanding and proficiency in molecular biology techniques (e.g. PCR, molecular cloning)
- Understanding of DNA sequencing techniques (NGS and Sanger) and sequence analysis
- Strong attention to quality and details when exercising organizational, documentation and communication skills
- Proven flexibility to deal with changing timelines and shifting work priorities
- Competency with software programs such as Geneious, Sequencher and MS Excel, PowerPoint, Word
Desirable:
- Experience with microfluidics and single cell analysis
- Experience with advanced automation platforms and programming
- Molecular biology techniques including molecular cloning
Position will be hired based on knowledge and/or level of experience.
Associate Scientist II or Scientist I
Additional Information
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
- We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is a considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is committed to operating with integrity, driving innovation, transforming lives, serving our community and embracing diversity and inclusion. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a protected veteran, or any other legally protected group status.
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