R&D Associate I

3 weeks ago

Worcester, United States University of Massachusetts Medical School Full time

Overview:

GENERAL SUMMARY OF POSITION:

The R&D Associate I - Product Discovery will be responsible for research and/or development to support early discovery and pre-clinical development of novel biotherapeutics. The ideal candidate will function in a cutting-edge laboratory environment as part of a multi-disciplinary team of protein engineers, immunologists, molecular biologists, and protein biochemists to discover novel therapeutics with opportunity to develop cGMP or GLP compliant skills in an industrial laboratory setting.

Responsibilities:

MAJOR RESPONSIBILITIES:

  • Drive translational research and development efforts by conducting experiments alongside R&D Scientists in the drug discovery department.
  • Conduct a wide range of biochemistry, molecular and cellular biology techniques to express, purify and characterize drug candidates (e.g. DNA/RNA isolation, plasmid construction, PCR, Octet, HPLC, mammalian cell culture, transient and stable transfections).
  • Perform in vitro assays to evaluate efficacy of drug candidates (e.g. ELISA, flow cytometry, cell proliferation, anti-microbial assays).
  • Assist experimental set up in small rodent animal models.
  • Analyze data and generate thorough documentation of work according to MassBiologics standards. Present written/oral reports in team meetings or other project meetings.
  • Maintain laboratory environment following all precautions required for a BSL2/BSL2+ setting. Troubleshoot malfunctioning equipment and techniques within scope of training.
  • Effectively communicate and work cross-functionally as a part of internal and external project teams.
  • Performs additional job related duties as required.


Qualifications:

REQUIRED QUALIFICATIONS:

  • Requires a bachelors degree in Biology or related field.
  • Minimum 0-2 years of relevant experience
  • Ability to follow instructions precisely , recognize deviations, and recommend corrective action within scope of training
  • Ability to troubleshoot within scope of training
  • Computer literate and proficient in MS Word, Excel and other relevant electronic systems.
  • Strong time management and organizational skills. Demonstrated ability to multitask and consistently meet deadlines
  • Ability to apply scientific principles to problem solving
  • Possesses well developed attention to detail, ability to maintain accurate records and excellent proofreading skills
  • Excellent written and verbal communication skills. Ability to communicate effectively with others
  • Demonstrated initiative through past experience
  • Working knowledge on protein purification and hands-on experience on chromatography workstations preferred
  • Ability to work effectively both independently and as a member of a team
  • May require individual to work extended hours on occasion to meet business needs

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