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Molecular Biology Research Specialist
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Molecular Biology Research Specialist
6 days ago
Cambridge, Massachusetts, United States Regel Therapeutics Full timePosition Title: Research Associate, Molecular BiologyCompany Overview: Regel Therapeutics is dedicated to advancing gene modulation therapies aimed at enhancing the quality of life for individuals affected by gene expression disorders. Our innovative T3 (Targeted Therapeutic Technology) platform integrates AAV delivery with proprietary methodologies to...
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Molecular Biology Research Specialist
6 days ago
Cambridge, Massachusetts, United States Regel Therapeutics Full timePosition Title: Research Associate in Molecular BiologyCompany Overview: Regel Therapeutics is a pioneering company in gene modulation therapy, dedicated to enhancing the lives of individuals affected by disorders linked to gene expression alterations. Our innovative T3 (Targeted Therapeutic Technology) platform integrates AAV delivery with proprietary...
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Molecular Biology Research Specialist
6 days ago
Cambridge, Massachusetts, United States Regel Therapeutics Full timePosition Title: Research Associate, Molecular BiologyCompany Overview: Regel Therapeutics is a pioneering company in gene modulation therapy, dedicated to enhancing the lives of individuals affected by disorders caused by gene expression alterations. Our innovative T3 (Targeted Therapeutic Technology) platform integrates AAV delivery with proprietary...
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Sr. Research Associate, Molecular Biology
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Molecular Biology Research Specialist
6 days ago
Cambridge, Massachusetts, United States Regel Therapeutics Full timePosition Title: Research Associate, Molecular BiologyCompany Overview: Regel Therapeutics is a pioneering company in gene modulation therapy, dedicated to enhancing the lives of individuals affected by disorders linked to gene expression alterations. Our innovative T3 (Targeted Therapeutic Technology) platform integrates AAV delivery with proprietary...
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Research Associate, Pluripotent Stem Cell Biology
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Research Associate, Stem Cell Biology
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Research Associate, Stem Cell Biology
2 days ago
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Senior Research Associate
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Research Associate, Stem Cell Biology
3 months ago
Cambridge, United States GC Therapeutics Full timeCompany OverviewGC Therapeutics is the first genome-wide cell landscape exploration company using an integrated synthetic biology and AI-driven platform for cell programming. Its patent-pending and proprietary pluripotent stem cell differentiation technology platform TFomeTM was developed in Professor George Church’s lab, a pioneer in synthetic biology,...
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Research Associate
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Cambridge, United States Regel Therapeutics Full timeResearch Associate, Molecular Biology - CambridgeRegel Therapeutics is a gene modulation therapy company focused on improving the life of patients suffering from disorders resulting from alteration of gene expression. Our proven T3 (Targeted Therapeutic Technology) platform combines AAV delivery with two proprietary technologies for efficient and specific...
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Research Associate
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Cambridge, United States Regel Therapeutics Full timeResearch Associate, Molecular Biology - CambridgeRegel Therapeutics is a gene modulation therapy company focused on improving the life of patients suffering from disorders resulting from alteration of gene expression. Our proven T3 (Targeted Therapeutic Technology) platform combines AAV delivery with two proprietary technologies for efficient and specific...
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Senior Research Associate, Process Development
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Research Associate/ Senior Research Associate
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Research Associate/ Senior Research Associate
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Research Scientist, Computational Biology
1 month ago
Cambridge, United States Penn Foster Inc Full timeScismic is supporting the growth of a Cambridge, MA biotech startup that is pioneering mRNA-modulating therapies to cure a broad range of genetic diseases. Job Description We are seeking a computational biologist with an innovative mindset, keen attention to detail, and the ability to work as part of a team to solve problems in preclinical research and...
Senior Research Associate, Molecular Biology
3 months ago
Platform & Target Discovery and ValidationCompany Overview
Repertoire Immune Medicines is a biotechnology company working to unlock and direct the remarkable power of the human immune system to treat cancer, autoimmune disease and infectious disease. The company was founded by Flagship Pioneering on the belief that understanding the repertoire of T cell receptor (TCR)-antigen immune synapses that maintain health and drive disease represents one of the greatest opportunities for innovation in medical science. Repertoire scientists created and developed the DECODETM platform, which allows in-depth characterization of TCR-antigen pairs, and the ability to deploy this information in the form of novel targeted immune medicines to fundamentally reprogram the immune system to kill tumors or induce immune homeostasis.
From its sites in Cambridge, Massachusetts and Zurich, Switzerland, Repertoire’s team is creating a new pipeline of therapeutic immune medicines enabled from its DECODE discovery platform. Repertoire is currently using its proprietary platform to discover novel epitopes and TCRs from patients with autoimmune diseases such as type 1 diabetes and multiple sclerosis, creating programmable tolerizing mRNA vaccines to restore immune homeostasis in these indications. In oncology, Repertoire’s decoding of tumor-infiltrating lymphocytes and the antigens they target is enabling development of TCR bispecific therapies and mRNA cancer vaccines to treat solid tumors.
On-site 5 days per week in Cambridge, MA
Role Overview
We are seeking a Senior Research Associate in the field of NGS and cell biology to join our Repertoire lab team. This individual will assist in the development, optimization, and validation of new or established assays to characterize T-cells in various conditions. We are looking for an enthusiastic team player who will thrive in a fast-paced, dynamic, and highly collaborative environment. This Senior Research Associate will work as part of a cross-functional team of immunologists, molecular biologists, and protein scientists to successfully develop and perform robust assays.
Key Responsibilities
- Perform routine molecular biology methodologies such as, but not limited to, nucleic acid extraction, library preparation for sequencing and qPCR.
- Culture and expand cell lines and perform in-vitro assays.
- Image and detect protein and RNA molecules in tissues and cells using various imaging systems.
- Participate or lead the development of new assays or optimize pre-existing methodologies.
- Develop and write protocols for assays.
- Analyze data and present key findings to internal stakeholders.
- Provide technical input and training to more junior team members.
- Execute and troubleshoot instrumentation, experiments, and data analysis.
- Work closely with team members to design and perform experiments.
- Report regularly on project progress.
- Present data effectively at internal group or project team meetings.
Qualifications/Experience
- Master’s degree or equivalent experience preferred in Genetics, Biochemistry, Cell Biology, or related discipline.
- Strong background in molecular biology and associated general laboratory techniques (PCR, qPCR, nucleic acid purification, NGS library preparation).
- Hands-on experience with mammalian cell culture and familiarity with protein related assays (Western blotting, ELISA, co-culture, flow cytometry) is preferred.
- Familiarity with molecular detection techniques such as immunofluorescence and in-situ hybridization. Exposure to microscopy imaging systems is a plus.
- Awareness of bioinformatics pipelines and sequencing metrics is desired.
- Impeccable documentation practices and attention to detail.
- Excellent written and verbal communication skills.
Repertoire is proud to be an Equal Opportunity Employer.
Recruitment & Staffing Agencies: Repertoire Immune Medicines (“Repertoire”) does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Repertoire or its employees is strictly prohibited unless contacted directly by Repertoire’s internal Human Resources team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Repertoire, and Repertoire will not owe any referral or other fees with respect thereto.
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