Senior Scientist, Biology

4 weeks ago

Waltham, United States Alloy Therapeutics Full time
Job DescriptionJob DescriptionThe Company
We are Alloy Therapeutics—a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to pre-competitive tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. The company facilitates affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech, to the largest biopharma. At Alloy, we believe our industry should compete on getting the best drugs to patients as quickly as possible, not exclusive access to the best platforms. As a reflection of our relentless commitment to the scientific community, we reinvest 100% of its revenue in innovation and access to innovation. MAY THE BEST DRUG WIN.

Alloy is headquartered in Waltham, MA with additional labs in Cambridge, UK; Basel, CH; and Athens, GA. Successful members thrive in our shared culture of accountability, deliberate trust, and open communication. As a team we aspire to work together to exceed expectations and collectively contribute across the global organization to always maintain our nimble, startup culture. Come thrive at Alloy

The Team 
The Alloy RNA Medicines group is innovating a novel RNA-based drug discovery platform, namely “AntiClastic”, spanning the fields of antisense therapeutics to immunomodulating therapeutics. The team works closely with external partners to discover and develop AntiClastic RNA medicines. 

The Role 
As a Senior Scientist, you will work within the RNA Medicine team to develop a novel nucleic acid drug development platform. You will also collaborate with internal/external partners on nucleic acid drug discovery projects to ensure timely execution of the experiments, and delivery of high-quality data. This role requires a self-starting behavior with an enthusiasm and passion to make medicines. This role will have an autonomy owning various stakeholders, projects, and tasks in a dynamic start-up environment while keeping up the pace of Alloy. This is you 

How You’ll Drive Impact 
  • Innovate: Lead multiple drug discovery and development projects. Develop novel methodologies to elucidate the mechanism of action of AntiClastic RNA Medicines
  • Improve: Learn and identify key questions in the RNA medicine area
  • Deliver: Spearhead drug discovery projects, Design, execute, analyze, and interpret in vitro and in vivo experiments. Generate robust, high-quality data.
  • Collaborate: Work closely with internal/external partners on drug discovery projects to ensure studies are executed to meet scientific goals and timelines.
Why We Value You 
  • You have a PhD or M.S. degree in Biology or related science with 5 to 8 years of additional experience in biotech/pharma.
  • Independently design, execute, and analyze in vitro experiments.
  • Strong understanding of antisense/siRNA research 
  • Ability to improve and develop new protocols/new assays to address key questions
  • Ability to interact and collaborate successfully in cross-functional teams
  • You have experience with RNA therapeutic development, from early discovery to pre-clinical development.
  • You have strong hands-on experience with molecular biology and protein techniques including, but not limited to, nucleic acid isolation, qPCR, RT-qPCR, western blots.
  • You have experience with cell culture and cell-based assays.
  • You have a keen attention for detail.
  • You have effective interpersonal skills, including both written and oral communication skills.
Desired Multipliers  
  • Excitement and willingness to learn.
  • Ability to work across various US and international time zones 
  • Accommodate occasional travel as needed (

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